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Molecular Tweezers: Supramolecular Hosts with Broad-Spectrum Biological Applications.
Shahpasand-Kroner H, Siddique I, Malik R, Linares GR, Ivanova MI, Ichida J, Weil T, Münch J, Sanchez-Garcia E, Klärner FG, Schrader T, Bitan G. Shahpasand-Kroner H, et al. Among authors: ivanova mi. Pharmacol Rev. 2023 Mar;75(2):263-308. doi: 10.1124/pharmrev.122.000654. Epub 2022 Dec 22. Pharmacol Rev. 2023. PMID: 36549866 Free PMC article. Review.
A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo.
Prabhudesai S, Sinha S, Attar A, Kotagiri A, Fitzmaurice AG, Lakshmanan R, Ivanova MI, Loo JA, Klärner FG, Schrader T, Stahl M, Bitan G, Bronstein JM. Prabhudesai S, et al. Among authors: ivanova mi. Neurotherapeutics. 2012 Apr;9(2):464-76. doi: 10.1007/s13311-012-0105-1. Neurotherapeutics. 2012. PMID: 22373667 Free PMC article.
Molecular basis for preventing α-synuclein aggregation by a molecular tweezer.
Acharya S, Safaie BM, Wongkongkathep P, Ivanova MI, Attar A, Klärner FG, Schrader T, Loo JA, Bitan G, Lapidus LJ. Acharya S, et al. Among authors: ivanova mi. J Biol Chem. 2014 Apr 11;289(15):10727-10737. doi: 10.1074/jbc.M113.524520. Epub 2014 Feb 24. J Biol Chem. 2014. PMID: 24567327 Free PMC article.
Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos.
Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Klärner FG, Schrader T, Sagasti A, Bronstein JM. Lulla A, et al. Among authors: ivanova mi. Environ Health Perspect. 2016 Nov;124(11):1766-1775. doi: 10.1289/EHP141. Epub 2016 Jun 15. Environ Health Perspect. 2016. PMID: 27301718 Free PMC article.
These findings have important implications for understanding the mechanisms by which pesticides may cause PD. Citation: Lulla A, Barnhill L, Bitan G, Ivanova MI, Nguyen B, O'Donnell K, Stahl MC, Yamashiro C, Klarner FG, Schrader T, Sagasti A, Bronstein JM. 2016. ...
These findings have important implications for understanding the mechanisms by which pesticides may cause PD. Citation: Lulla A, Barnhill L, …
High-Throughput Screening at the Membrane Interface Reveals Inhibitors of Amyloid-β.
Cox SJ, Lam B, Prasad A, Marietta HA, Stander NV, Joel JG, Sahoo BR, Guo F, Stoddard AK, Ivanova MI, Ramamoorthy A. Cox SJ, et al. Among authors: ivanova mi. Biochemistry. 2020 Jun 23;59(24):2249-2258. doi: 10.1021/acs.biochem.0c00328. Epub 2020 Jun 5. Biochemistry. 2020. PMID: 32469202 Free PMC article.
Structure-based design of functional amyloid materials.
Li D, Jones EM, Sawaya MR, Furukawa H, Luo F, Ivanova M, Sievers SA, Wang W, Yaghi OM, Liu C, Eisenberg DS. Li D, et al. J Am Chem Soc. 2014 Dec 31;136(52):18044-51. doi: 10.1021/ja509648u. Epub 2014 Dec 19. J Am Chem Soc. 2014. PMID: 25474758
Small molecule induced toxic human-IAPP species characterized by NMR.
Cox SJ , Rodriguez Camargo DC , Lee YH , Dubini RCA , Rovó P , Ivanova MI , Padmini V , Reif B , Ramamoorthy A . Cox SJ , et al. Among authors: ivanova mi. Chem Commun (Camb). 2020 Nov 7;56(86):13129-13132. doi: 10.1039/d0cc04803h. Epub 2020 Oct 2. Chem Commun (Camb). 2020. PMID: 33006345 Free PMC article.
58 results