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Safety and Tolerability of SRX246, a Vasopressin 1a Antagonist, in Irritable Huntington's Disease Patients-A Randomized Phase 2 Clinical Trial.
Brownstein MJ, Simon NG, Long JD, Yankey J, Maibach HT, Cudkowicz M, Coffey C, Conwit RA, Lungu C, Anderson KE, Hersch SM, Ecklund DJ, Damiano EM, Itzkowitz DE, Lu S, Chase MK, Shefner JM, McGarry A, Thornell B, Gladden C, Costigan M, O'Suilleabhain P, Marshall FJ, Chesire AM, Deritis P, Adams JL, Hedera P, Lowen K, Rosas HD, Hiller AL, Quinn J, Keith K, Duker AP, Gruenwald C, Molloy A, Jacob C, Factor S, Sperin E, Bega D, Brown ZR, Seeberger LC, Sung VW, Benge M, Kostyk SK, Daley AM, Perlman S, Suski V, Conlon P, Barrett MJ, Lowenhaupt S, Quigg M, Perlmutter JS, Wright BA, Most E, Schwartz GJ, Lamb J, Chuang RS, Singer C, Marder K, Moran JA, Singleton JR, Zorn M, Wall PV, Dubinsky RM, Gray C, Drazinic C. Brownstein MJ, et al. Among authors: itzkowitz de. J Clin Med. 2020 Nov 16;9(11):3682. doi: 10.3390/jcm9113682. J Clin Med. 2020. PMID: 33207828 Free PMC article.
A proof-of-concept randomized crossover clinical trial of a first-in-class vasopressin 1a receptor antagonist for PTSD: Design, methods, and recruitment.
Difede J, McAleavey AA, Emrich M, Jick A, Ovalles A, Wyka K, Spielman L, Olden M, Peskin M, Becket-Davenport C, Rubenstein A, Brownstein MJ, Damiano E, Itzkowitz D, Lu SF, Needell NJ, Kocsis JH, Gordon-Elliott JS, Simon NG. Difede J, et al. Contemp Clin Trials Commun. 2023 Mar 17;33:101116. doi: 10.1016/j.conctc.2023.101116. eCollection 2023 Jun. Contemp Clin Trials Commun. 2023. PMID: 37008794 Free PMC article.