Itzen A - Search Results

1

The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3.

Höpfner D, Cichy A, Pogenberg V, Krisp C, Mezouar S, Bach NC, Grotheer J, Zarza SM, Martinez E, Bonazzi M, Feige MJ, Sieber SA, Schlüter H, Itzen A. Höpfner D, et al. Among authors: itzen a. Commun Biol. 2023 Nov 6;6(1):1124. doi: 10.1038/s42003-023-05494-7. Commun Biol. 2023. PMID: 37932372 Free PMC article.

2

Protein LidA from Legionella is a Rab GTPase supereffector.

Schoebel S, Cichy AL, Goody RS, Itzen A. Schoebel S, et al. Among authors: itzen a. Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):17945-50. doi: 10.1073/pnas.1113133108. Epub 2011 Oct 19. Proc Natl Acad Sci U S A. 2011. PMID: 22011575 Free PMC article.

3

The Legionella longbeachae Icm/Dot substrate SidC selectively binds phosphatidylinositol 4-phosphate with nanomolar affinity and promotes pathogen vacuole-endoplasmic reticulum interactions.

Dolinsky S, Haneburger I, Cichy A, Hannemann M, Itzen A, Hilbi H. Dolinsky S, et al. Among authors: itzen a. Infect Immun. 2014 Oct;82(10):4021-33. doi: 10.1128/IAI.01685-14. Epub 2014 Jul 14. Infect Immun. 2014. PMID: 25024371 Free PMC article.

4

Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture.

Gulen B, Rosselin M, Fauser J, Albers MF, Pett C, Krisp C, Pogenberg V, Schlüter H, Hedberg C, Itzen A. Gulen B, et al. Among authors: itzen a. Nat Chem. 2020 Aug;12(8):732-739. doi: 10.1038/s41557-020-0484-6. Epub 2020 Jul 6. Nat Chem. 2020. PMID: 32632184

5

Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation.

Höpfner D, Fauser J, Kaspers MS, Pett C, Hedberg C, Itzen A. Höpfner D, et al. Among authors: itzen a. iScience. 2020 Nov 13;23(12):101800. doi: 10.1016/j.isci.2020.101800. eCollection 2020 Dec 18. iScience. 2020. PMID: 33299971 Free PMC article.

6

Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1.

Du J, Wrisberg MV, Gulen B, Stahl M, Pett C, Hedberg C, Lang K, Schneider S, Itzen A. Du J, et al. Among authors: itzen a. Nat Commun. 2021 Jan 19;12(1):460. doi: 10.1038/s41467-020-20702-2. Nat Commun. 2021. PMID: 33469029 Free PMC article.

7

Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD.

Fauser J, Gulen B, Pogenberg V, Pett C, Pourjafar-Dehkordi D, Krisp C, Höpfner D, König G, Schlüter H, Feige MJ, Zacharias M, Hedberg C, Itzen A. Fauser J, et al. Among authors: itzen a. Nat Commun. 2021 Apr 23;12(1):2426. doi: 10.1038/s41467-021-22596-0. Nat Commun. 2021. PMID: 33893288 Free PMC article.

8

Erratum: Monoclonal Anti-AMP Antibodies Are Sensitive and Valuable Tools for Detecting Patterns of AMPylation.

Höpfner D, Fauser J, Kaspers MS, Pett C, Hedberg C, Itzen A. Höpfner D, et al. Among authors: itzen a. iScience. 2021 Jun 26;24(7):102731. doi: 10.1016/j.isci.2021.102731. eCollection 2021 Jul 23. iScience. 2021. PMID: 34235414 Free PMC article.

9

Revisiting AMPylation through the lens of Fic enzymes.

Gulen B, Itzen A. Gulen B, et al. Among authors: itzen a. Trends Microbiol. 2022 Apr;30(4):350-363. doi: 10.1016/j.tim.2021.08.003. Epub 2021 Sep 13. Trends Microbiol. 2022. PMID: 34531089 Review.

10

Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b.

Kaspers MS, Pogenberg V, Pett C, Ernst S, Ecker F, Ochtrop P, Groll M, Hedberg C, Itzen A. Kaspers MS, et al. Among authors: itzen a. Nat Commun. 2023 Apr 19;14(1):2245. doi: 10.1038/s41467-023-37621-7. Nat Commun. 2023. PMID: 37076474 Free PMC article.

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