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Developmental exposure to diacetoxyscirpenol reversibly disrupts hippocampal neurogenesis by inducing oxidative cellular injury and suppressed differentiation of granule cell lineages in mice.
Nakajima K, Ito Y, Kikuchi S, Okano H, Takashima K, Woo GH, Yoshida T, Yoshinari T, Sugita-Konishi Y, Shibutani M. Nakajima K, et al. Among authors: ito y. Food Chem Toxicol. 2020 Feb;136:111046. doi: 10.1016/j.fct.2019.111046. Epub 2019 Dec 10. Food Chem Toxicol. 2020. PMID: 31836554 Free article.
Downregulation of UBE2E2 in rat liver cells after hepatocarcinogen treatment facilitates cell proliferation and slowing down of DNA damage response in GST-P-expressing preneoplastic lesions.
Mizukami S, Watanabe Y, Saegusa Y, Nakajima K, Ito Y, Masubuchi Y, Yoshida T, Shibutani M. Mizukami S, et al. Among authors: ito y. Toxicol Appl Pharmacol. 2017 Nov 1;334:207-216. doi: 10.1016/j.taap.2017.09.005. Epub 2017 Sep 9. Toxicol Appl Pharmacol. 2017. PMID: 28899750
Lack of preventive effect of maternal exposure to α-glycosyl isoquercitrin and α-lipoic acid on developmental hypothyroidism-induced aberrations of hippocampal neurogenesis in rat offspring.
Masubuchi Y, Tanaka T, Okada R, Ito Y, Nakahara J, Kikuchi S, Watanabe Y, Yoshida T, Maronpot RR, Koyanagi M, Hayashi SM, Shibutani M. Masubuchi Y, et al. Among authors: ito y. J Toxicol Pathol. 2019 Jul;32(3):165-180. doi: 10.1293/tox.2019-0018. Epub 2019 May 31. J Toxicol Pathol. 2019. PMID: 31404398 Free PMC article.
Downregulation of low-density lipoprotein receptor class A domain-containing protein 4 (Ldlrad4) in the liver of rats treated with nongenotoxic hepatocarcinogen to induce transforming growth factor β signaling promoting cell proliferation and suppressing apoptosis in early hepatocarcinogenesis.
Ito Y, Nakajima K, Masubuchi Y, Kikuchi S, Okano H, Saito F, Akahori Y, Jin M, Yoshida T, Shibutani M. Ito Y, et al. J Appl Toxicol. 2020 Nov;40(11):1467-1479. doi: 10.1002/jat.3998. Epub 2020 Jun 28. J Appl Toxicol. 2020. PMID: 32596862
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