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Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis.
Kikuchi K, Setoyama K, Kawahara KI, Nagasato T, Terashi T, Ueda K, Nakanishi K, Otsuka S, Miura N, Sameshima H, Hosokawa K, Harada Y, Shrestha B, Yamamoto M, Morimoto-Yamashita Y, Kikuchi H, Kiyama R, Kamikokuryo C, Tancharoen S, Sakakima H, Morioka M, Tanaka E, Ito T, Maruyama I. Kikuchi K, et al. Among authors: ito t. Oxid Med Cell Longev. 2017;2017:6873281. doi: 10.1155/2017/6873281. Epub 2017 Nov 10. Oxid Med Cell Longev. 2017. PMID: 29259732 Free PMC article.
HMGB1 release in co-cultures of porcine endothelial and human T cells.
Kawahara K, Setoyama K, Kikuchi K, Biswas KK, Kamimura R, Iwata M, Ito T, Morimoto Y, Hashiguchi T, Takao S, Maruyama I. Kawahara K, et al. Among authors: ito t. Xenotransplantation. 2007 Nov;14(6):636-41. doi: 10.1111/j.1399-3089.2007.00434.x. Xenotransplantation. 2007. PMID: 17991152
C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells.
Kawahara K, Biswas KK, Unoshima M, Ito T, Kikuchi K, Morimoto Y, Iwata M, Tancharoen S, Oyama Y, Takenouchi K, Nawa Y, Arimura N, Jie MX, Shrestha B, Miura N, Shimizu T, Mera K, Arimura S, Taniguchi N, Iwasaka H, Takao S, Hashiguchi T, Maruyama I. Kawahara K, et al. Among authors: ito t. Cardiovasc Pathol. 2008 May-Jun;17(3):129-38. doi: 10.1016/j.carpath.2007.08.006. Epub 2007 Oct 24. Cardiovasc Pathol. 2008. PMID: 18402807
Thrombomodulin exerts cytoprotective effect on low-dose UVB-irradiated HaCaT cells.
Iwata M, Kawahara KI, Kawabata H, Ito T, Mera K, Biswas KK, Tancharoen S, Higashi Y, Kikuchi K, Hashiguchi T, Kanekura T, Maruyama I. Iwata M, et al. Among authors: ito t. Biochem Biophys Res Commun. 2008 Dec 12;377(2):642-647. doi: 10.1016/j.bbrc.2008.10.049. Epub 2008 Oct 20. Biochem Biophys Res Commun. 2008. PMID: 18940182
The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.
Kikuchi K, Kawahara K, Tancharoen S, Matsuda F, Morimoto Y, Ito T, Biswas KK, Takenouchi K, Miura N, Oyama Y, Nawa Y, Arimura N, Iwata M, Tajima Y, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I. Kikuchi K, et al. Among authors: ito t. J Pharmacol Exp Ther. 2009 Jun;329(3):865-74. doi: 10.1124/jpet.108.149484. Epub 2009 Mar 17. J Pharmacol Exp Ther. 2009. PMID: 19293391
Mechanism of HMGB1 release inhibition from RAW264.7 cells by oleanolic acid in Prunus mume Sieb. et Zucc.
Kawahara K, Hashiguchi T, Masuda K, Saniabadi AR, Kikuchi K, Tancharoen S, Ito T, Miura N, Morimoto Y, Biswas KK, Nawa Y, Meng X, Oyama Y, Takenouchi K, Shrestha B, Sameshima H, Shimizu T, Adachi T, Adachi M, Maruyama I. Kawahara K, et al. Among authors: ito t. Int J Mol Med. 2009 May;23(5):615-20. doi: 10.3892/ijmm_00000172. Int J Mol Med. 2009. PMID: 19360320
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