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Optineurin suppression causes neuronal cell death via NF-κB pathway.
Akizuki M, Yamashita H, Uemura K, Maruyama H, Kawakami H, Ito H, Takahashi R. Akizuki M, et al. Among authors: ito h. J Neurochem. 2013 Sep;126(6):699-704. doi: 10.1111/jnc.12326. Epub 2013 Jun 17. J Neurochem. 2013. PMID: 23721573 Free article.
Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation.
Ito H, Nakamura M, Komure O, Ayaki T, Wate R, Maruyama H, Nakamura Y, Fujita K, Kaneko S, Okamoto Y, Ihara M, Konishi T, Ogasawara K, Hirano A, Kusaka H, Kaji R, Takahashi R, Kawakami H. Ito H, et al. Acta Neuropathol. 2011 Aug;122(2):223-9. doi: 10.1007/s00401-011-0842-y. Epub 2011 Jun 5. Acta Neuropathol. 2011. PMID: 21644038
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