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RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia.
Gialesaki S, Bräuer-Hartmann D, Issa H, Bhayadia R, Alejo-Valle O, Verboon L, Schmell AL, Laszig S, Regényi E, Schuschel K, Labuhn M, Ng M, Winkler R, Ihling C, Sinz A, Glaß M, Hüttelmaier S, Matzk S, Schmid L, Strüwe FJ, Kadel SK, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Gialesaki S, et al. Among authors: issa h. Blood. 2023 Mar 9;141(10):1105-1118. doi: 10.1182/blood.2022017619. Blood. 2023. PMID: 36493345 Free PMC article.
The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation.
Martinez-Soria N, McKenzie L, Draper J, Ptasinska A, Issa H, Potluri S, Blair HJ, Pickin A, Isa A, Chin PS, Tirtakusuma R, Coleman D, Nakjang S, Assi S, Forster V, Reza M, Law E, Berry P, Mueller D, Osborne C, Elder A, Bomken SN, Pal D, Allan JM, Veal GJ, Cockerill PN, Wichmann C, Vormoor J, Lacaud G, Bonifer C, Heidenreich O. Martinez-Soria N, et al. Among authors: issa h. Cancer Cell. 2019 Apr 15;35(4):705. doi: 10.1016/j.ccell.2019.03.012. Cancer Cell. 2019. PMID: 30991028 Free PMC article. No abstract available.
The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis.
Alejo-Valle O, Weigert K, Bhayadia R, Ng M, Issa H, Beyer C, Emmrich S, Schuschel K, Ihling C, Sinz A, Zimmermann M, Wickenhauser C, Flasinski M, Regenyi E, Labuhn M, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Alejo-Valle O, et al. Among authors: issa h. Blood. 2022 Feb 3;139(5):651-665. doi: 10.1182/blood.2021012231. Blood. 2022. PMID: 34570885 Free PMC article.
Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15.
Ng M, Verboon L, Issa H, Bhayadia R, Vermunt MW, Winkler R, Schüler L, Alejo O, Schuschel K, Regenyi E, Borchert D, Heuser M, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. Ng M, et al. Among authors: issa h. iScience. 2023 Sep 7;26(10):107844. doi: 10.1016/j.isci.2023.107844. eCollection 2023 Oct 20. iScience. 2023. PMID: 37766974 Free PMC article.
The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation.
Martinez-Soria N, McKenzie L, Draper J, Ptasinska A, Issa H, Potluri S, Blair HJ, Pickin A, Isa A, Chin PS, Tirtakusuma R, Coleman D, Nakjang S, Assi S, Forster V, Reza M, Law E, Berry P, Mueller D, Osborne C, Elder A, Bomken SN, Pal D, Allan JM, Veal GJ, Cockerill PN, Wichmann C, Vormoor J, Lacaud G, Bonifer C, Heidenreich O. Martinez-Soria N, et al. Among authors: issa h. Cancer Cell. 2018 Oct 8;34(4):626-642.e8. doi: 10.1016/j.ccell.2018.08.015. Cancer Cell. 2018. PMID: 30300583 Free PMC article.
A robust post-insertion method for the preparation of targeted siRNA LNPs.
Swart LE, Koekman CA, Seinen CW, Issa H, Rasouli M, Schiffelers RM, Heidenreich O. Swart LE, et al. Among authors: issa h. Int J Pharm. 2022 May 25;620:121741. doi: 10.1016/j.ijpharm.2022.121741. Epub 2022 Apr 11. Int J Pharm. 2022. PMID: 35421533 Free article.
Tob Regulates the Timing of Sleep Onset at Night in Drosophila.
Han E, Lee SS, Park KH, Blum ID, Liu Q, Mehta A, Palmer I, Issa H, Han A, Brown MP, Sanchez-Franco VM, Velasco M, Tabuchi M, Wu MN. Han E, et al. Among authors: issa h. J Neurosci. 2024 May 1;44(18):e0389232024. doi: 10.1523/JNEUROSCI.0389-23.2024. J Neurosci. 2024. PMID: 38485259
215 results