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Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.
Fujino T, Goyama S, Sugiura Y, Inoue D, Asada S, Yamasaki S, Matsumoto A, Yamaguchi K, Isobe Y, Tsuchiya A, Shikata S, Sato N, Morinaga H, Fukuyama T, Tanaka Y, Fukushima T, Takeda R, Yamamoto K, Honda H, Nishimura EK, Furukawa Y, Shibata T, Abdel-Wahab O, Suematsu M, Kitamura T. Fujino T, et al. Among authors: isobe y. Nat Commun. 2021 Mar 23;12(1):1826. doi: 10.1038/s41467-021-22053-y. Nat Commun. 2021. PMID: 33758188 Free PMC article.
Identification of odontogenic ameloblast associated as a novel target gene of the Wnt/β-catenin signaling pathway.
Yamaguchi K, Horie C, Takane K, Ikenoue T, Nakagawa S, Isobe Y, Ota Y, Ushiku T, Tanaka M, Fujishiro J, Hoshino N, Arisue A, Nishizuka S, Aikou S, Shida D, Furukawa Y. Yamaguchi K, et al. Among authors: isobe y. Cancer Sci. 2023 Mar;114(3):948-960. doi: 10.1111/cas.15657. Epub 2022 Nov 29. Cancer Sci. 2023. PMID: 36382598 Free PMC article.
Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex.
Yamaguchi K, Nakagawa S, Saku A, Isobe Y, Yamaguchi R, Sheridan P, Takane K, Ikenoue T, Zhu C, Miura M, Okawara Y, Nagatoishi S, Kozuka-Hata H, Oyama M, Aikou S, Ahiko Y, Shida D, Tsumoto K, Miyano S, Imoto S, Furukawa Y. Yamaguchi K, et al. Among authors: isobe y. iScience. 2023 Apr 1;26(4):106563. doi: 10.1016/j.isci.2023.106563. eCollection 2023 Apr 21. iScience. 2023. PMID: 37123243 Free PMC article.
Design, synthesis, and biological activity of novel factor Xa inhibitors: improving metabolic stability by S1 and S4 ligand modification.
Komoriya S, Kobayashi S, Osanai K, Yoshino T, Nagata T, Haginoya N, Nakamoto Y, Mochizuki A, Nagahara T, Suzuki M, Shimada T, Watanabe K, Isobe Y, Furugoori T. Komoriya S, et al. Among authors: isobe y. Bioorg Med Chem. 2006 Mar 1;14(5):1309-30. doi: 10.1016/j.bmc.2005.09.056. Epub 2005 Nov 2. Bioorg Med Chem. 2006. PMID: 16263291
Integration of Kupffer cells into human iPSC-derived liver organoids for modeling liver dysfunction in sepsis.
Li Y, Nie Y, Yang X, Liu Y, Deng X, Hayashi Y, Plummer R, Li Q, Luo N, Kasai T, Okumura T, Kamishibahara Y, Komoto T, Ohkuma T, Okamoto S, Isobe Y, Yamaguchi K, Furukawa Y, Taniguchi H. Li Y, et al. Among authors: isobe y. Cell Rep. 2024 Mar 26;43(3):113918. doi: 10.1016/j.celrep.2024.113918. Epub 2024 Mar 6. Cell Rep. 2024. PMID: 38451817 Free article.
516 results