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Delivery of a BET protein degrader via a CEACAM6-targeted antibody-drug conjugate inhibits tumour growth in pancreatic cancer models.
Nakazawa Y, Miyano M, Tsukamoto S, Kogai H, Yamamoto A, Iso K, Inoue S, Yamane Y, Yabe Y, Umihara H, Taguchi J, Akagi T, Yamaguchi A, Koga M, Toshimitsu K, Hirayama T, Mukai Y, Machinaga A. Nakazawa Y, et al. Among authors: iso k. Nat Commun. 2024 Mar 11;15(1):2192. doi: 10.1038/s41467-024-46167-1. Nat Commun. 2024. PMID: 38467634 Free PMC article.
Targeted protein degradation via intramolecular bivalent glues.
Hsia O, Hinterndorfer M, Cowan AD, Iso K, Ishida T, Sundaramoorthy R, Nakasone MA, Imrichova H, Schätz C, Rukavina A, Husnjak K, Wegner M, Correa-Sáez A, Craigon C, Casement R, Maniaci C, Testa A, Kaulich M, Dikic I, Winter GE, Ciulli A. Hsia O, et al. Among authors: iso k. Nature. 2024 Mar;627(8002):204-211. doi: 10.1038/s41586-024-07089-6. Epub 2024 Feb 21. Nature. 2024. PMID: 38383787 Free PMC article.
Ten-Gram-Scale Total Synthesis of the Anticancer Drug Candidate E7130 to Supply Clinical Trials.
Kaburagi Y, Kira K, Yahata K, Iso K, Sato Y, Matsuura F, Ohashi I, Matsumoto Y, Isomura M, Sasaki T, Fukuyama T, Miyashita Y, Azuma H, Iida D, Ishida T, Itano W, Matsuda M, Matsukura M, Murai N, Nagao S, Seki M, Yamamoto A, Yamamoto Y, Yoneda N, Watanabe Y, Kamada A, Kayano A, Tagami K, Asano O, Owa T, Kishi Y. Kaburagi Y, et al. Among authors: iso k. Org Lett. 2024 Apr 12;26(14):2837-2842. doi: 10.1021/acs.orglett.3c03663. Epub 2024 Jan 22. Org Lett. 2024. PMID: 38252895
Tumor-suppressive role of the musculoaponeurotic fibrosarcoma gene in colorectal cancer.
Itakura H, Hata T, Okuzaki D, Takeda K, Iso K, Qian Y, Morimoto Y, Adachi T, Hirose H, Yokoyama Y, Ogino T, Miyoshi N, Takahashi H, Uemura M, Mizushima T, Hinoi T, Mori M, Doki Y, Eguchi H, Yamamoto H. Itakura H, et al. Among authors: iso k. iScience. 2023 Mar 23;26(4):106478. doi: 10.1016/j.isci.2023.106478. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091240 Free PMC article.
Registry for Evaluating Healthy Life Expectancy and Long-Term Outcomes after Catheter Ablation of Atrial Fibrillation in the Very Elderly (REHEALTH AF) study: rationale and design of a prospective, multicentre, observational, comparative study.
Okumura Y, Nagashima K, Watanabe R, Yokoyama K, Kato T, Fukaya H, Hayashi H, Nakahara S, Shimizu W, Iwasaki YK, Fujimoto Y, Mukai Y, Ejima K, Otsuka T, Suzuki S, Murakami M, Kimura M, Harada M, Koyama J, Okamatsu H, Yamane T, Yamashita S, Tokuda M, Narui R, Takami M, Shoda M, Harada T, Nakajima I, Fujiu K, Hiroshima K, Tanimoto K, Fujino T, Nakamura K, Kumagai K, Okada A, Kobayashi H, Hayashi T, Watari Y, Hatsuno M, Tachibana E, Iso K, Sonoda K, Aizawa Y, Chikata A, Sakagami S, Inoue M, Minamiguchi H, Makino N, Satomi K, Yazaki Y, Aoyagi H, Ichikawa M, Haruta H, Hiro T, Okubo K, Arima K, Tojo T, Kihara H, Miyanaga S, Fukuda Y, Oiwa K, Fujiishi T, Akabane M, Ishikawa N, Kusano K, Miyamoto K, Tabuchi H, Shiozawa T, Miyamoto K, Mase H, Murotani K; REHEALTH AF study. Okumura Y, et al. Among authors: iso k. BMJ Open. 2023 Feb 15;13(2):e068894. doi: 10.1136/bmjopen-2022-068894. BMJ Open. 2023. PMID: 36792334 Free PMC article.
Variation in blood pressure and heart rate of radiological technologists in worktime tracked by a wearable device: A preliminary study.
Minamimoto R, Yamada Y, Sugawara Y, Fujii M, Kotabe K, Iso K, Yokoyama H, Kurihara K, Iwasaki T, Horikawa D, Saito K, Kajiwara H, Matsunaga F. Minamimoto R, et al. Among authors: iso k. PLoS One. 2022 Nov 17;17(11):e0276483. doi: 10.1371/journal.pone.0276483. eCollection 2022. PLoS One. 2022. PMID: 36395333 Free PMC article.
A troubling tachycardia.
Hayashida S, Nagashima K, Iso K, Okumura Y, Scheinman MM. Hayashida S, et al. Among authors: iso k. Heart Rhythm. 2022 Jun;19(6):1031-1032. doi: 10.1016/j.hrthm.2021.09.001. Heart Rhythm. 2022. PMID: 35636839 No abstract available.
93 results