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Design, synthesis, anti-proliferative evaluation, docking, and MD simulation studies of new thieno[2,3-d]pyrimidines targeting VEGFR-2.
El-Metwally SA, Elkady H, Hagras M, Husein DZ, Ibrahim IM, Taghour MS, El-Mahdy HA, Ismail A, Alsfouk BA, Elkaeed EB, Metwaly AM, Eissa IH. El-Metwally SA, et al. Among authors: ismail a. RSC Adv. 2023 Aug 4;13(33):23365-23385. doi: 10.1039/d3ra03128d. eCollection 2023 Jul 26. RSC Adv. 2023. PMID: 37545598 Free PMC article.
In vitro and in silico evaluation of new thieno[2,3-d]pyrimidines as anti-cancer agents and apoptosis inducers targeting VEGFR-2.
El-Metwally SA, Abuelkhir AA, Elkady H, Taghour MS, Ibrahim IM, Husein DZ, Alsfouk AA, Sultan A, Ismail A, Elkhawaga SY, Elkaeed EB, Metwaly AM, Eissa IH. El-Metwally SA, et al. Among authors: ismail a. Comput Biol Chem. 2023 Oct;106:107928. doi: 10.1016/j.compbiolchem.2023.107928. Epub 2023 Jul 18. Comput Biol Chem. 2023. PMID: 37480629
New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies.
Elkady H, Elwan A, El-Mahdy HA, Doghish AS, Ismail A, Taghour MS, Elkaeed EB, Eissa IH, Dahab MA, Mahdy HA, Khalifa MM. Elkady H, et al. Among authors: ismail a. J Enzyme Inhib Med Chem. 2022 Dec;37(1):397-410. doi: 10.1080/14756366.2021.2015343. J Enzyme Inhib Med Chem. 2022. PMID: 34961427 Free PMC article.
Synthesis, biological evaluation, and in silico studies of new CDK2 inhibitors based on pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold with apoptotic activity.
Mandour AA, Nassar IF, Abdel Aal MT, Shahin MAE, El-Sayed WA, Hegazy M, Yehia AM, Ismail A, Hagras M, Elkaeed EB, Refaat HM, Ismail NSM. Mandour AA, et al. Among authors: ismail nsm, ismail a. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1957-1973. doi: 10.1080/14756366.2022.2086866. J Enzyme Inhib Med Chem. 2022. PMID: 35815597 Free PMC article.
Possible role of miRNAs in pheochromocytoma pathology - Signaling pathways interaction.
Elkhawaga SY, Elshafei A, Elkady MA, Yehia AM, Abulsoud AI, Abdelmaksoud NM, Elsakka EGE, Ismail A, Mokhtar MM, El-Mahdy HA, Hegazy M, Elballal MS, Mohammed OA, Abdel-Reheim MA, El-Dakroury WA, Abdel Mageed SS, Elrebehy MA, Shahin RK, Zaki MB, Doghish AS. Elkhawaga SY, et al. Among authors: ismail a. Pathol Res Pract. 2023 Nov;251:154856. doi: 10.1016/j.prp.2023.154856. Epub 2023 Oct 5. Pathol Res Pract. 2023. PMID: 37806171 Review.
From diagnosis to resistance: a symphony of miRNAs in pheochromocytoma progression and treatment response.
Elsakka EGE, Elshafei A, Elkady MA, Yehia AM, Abulsoud AI, Shahin RK, Abdelmaksoud NM, Elkhawaga SY, Ismail A, Mokhtar MM, Elrebehy MA, Hegazy M, Elballal MS, Mohammed OA, Abdel-Reheim MA, El-Dakroury WA, Abdel Mageed SS, El-Mahdy HA, Doghish AS. Elsakka EGE, et al. Among authors: ismail a. Naunyn Schmiedebergs Arch Pharmacol. 2024 Apr;397(4):1957-1969. doi: 10.1007/s00210-023-02759-0. Epub 2023 Oct 6. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 37801146 Review.
3,071 results