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Synthesis of Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via a One-Pot (Ugi-3CR/aza Diels-Alder/N-acylation/aromatization/SN2) Process. A Suitable Alternative towards Novel Aza-Analogues of Falipamil.
Zamudio-Medina A, García-González AN, Herrera-Carrillo GK, Zárate-Zárate D, Benavides-Macías A, Tamariz J, Ibarra IA, Islas-Jácome A, González-Zamora E. Zamudio-Medina A, et al. Molecules. 2018 Mar 27;23(4):763. doi: 10.3390/molecules23040763. Molecules. 2018. PMID: 29584639 Free PMC article.
Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Multicomponent Reactions and In Vitro-In Silico Studies Against SiHa, HeLa, and CaSki Human Cervical Carcinoma Cell Lines.
Segura-Olvera D, García-González AN, Morales-Salazar I, Islas-Jácome A, Rojas-Aguirre Y, Ibarra IA, Díaz-Cervantes E, Alcaraz-Estrada SL, González-Zamora E. Segura-Olvera D, et al. Molecules. 2019 Jul 22;24(14):2648. doi: 10.3390/molecules24142648. Molecules. 2019. PMID: 31336585 Free PMC article.
Quadratic Non-Linear Optical Properties of the poly(2,5-bis(but-2-ynyloxy) Benzoate Containing the 2-(ethyl(4-((4-nitrophenyl)buta-1,3-diynyl)phenyl)amino)ethanol) Chromophore.
Castañón-Alonso SL, Morales-Saavedra OG, Almaraz-Girón MA, Báez-Pimiento S, Islas-Jácome A, Rocha-Ramírez LM, Domínguez-Ortiz A, Esparza-Schulz M, Romero-Galarza A, Hernández-Rojas ME. Castañón-Alonso SL, et al. Among authors: islas jacome a. Polymers (Basel). 2020 Jan 20;12(1):241. doi: 10.3390/polym12010241. Polymers (Basel). 2020. PMID: 31968552 Free PMC article.
A One-Pot Six-Component Reaction for the Synthesis of 1,5-Disubstituted Tetrazol-1,2,3-Triazole Hybrids and Their Cytotoxic Activity against the MCF-7 Cell Line.
Aguilar-Morales CM, Araujo-Huitrado JG, López-Hernández Y, Contreras-Celedón C, Islas-Jácome A, Granados-López AJ, Solorio-Alvarado CR, López JA, Chacón-García L, Cortés-García CJ. Aguilar-Morales CM, et al. Among authors: islas jacome a. Molecules. 2021 Oct 10;26(20):6104. doi: 10.3390/molecules26206104. Molecules. 2021. PMID: 34684686 Free PMC article.
Synthesis of bis-furyl-pyrrolo[3,4-b]pyridin-5-ones via Ugi-Zhu reaction and in vitro activity assays against human SARS-CoV-2 and in silico studies on its main proteins.
Morales-Salazar I, Montes-Enríquez FP, Garduño-Albino CE, García-Sánchez MA, Ibarra IA, Rojas-Aguirre Y, García-Hernández ME, Sarmiento-Silva RE, Alcaraz-Estrada SL, Díaz-Cervantes E, González-Zamora E, Islas-Jácome A. Morales-Salazar I, et al. Among authors: islas jacome a. RSC Med Chem. 2022 Nov 18;14(1):154-165. doi: 10.1039/d2md00350c. eCollection 2023 Jan 25. RSC Med Chem. 2022. PMID: 36760742 Free PMC article.
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