Ishihara K - Search Results

1

[Comprehensive Analyses of Molecules with Altered Expression in the Brain of a Mouse Model of Down Syndrome for Identification of Pharmacotherapeutic Targets].

Ishihara K. Ishihara K. Yakugaku Zasshi. 2017;137(7):807-810. doi: 10.1248/yakushi.16-00236-3. Yakugaku Zasshi. 2017. PMID: 28674291 Free article. Review. Japanese.

2

[Identification of molecules with altered expression in the brain of mouse model for Down syndrome by comprehensive analyses].

Ishihara K. Ishihara K. Yakugaku Zasshi. 2013;133(9):989-94. doi: 10.1248/yakushi.13-00167. Yakugaku Zasshi. 2013. PMID: 23995807 Free article. Review. Japanese.

3

Comparative proteomic profiling reveals aberrant cell proliferation in the brain of embryonic Ts1Cje, a mouse model of Down syndrome.

Ishihara K, Kanai S, Sago H, Yamakawa K, Akiba S. Ishihara K, et al. Neuroscience. 2014 Dec 5;281:1-15. doi: 10.1016/j.neuroscience.2014.09.039. Epub 2014 Sep 28. Neuroscience. 2014. PMID: 25261685

4

Brain ventriculomegaly in Down syndrome mice is caused by Pcp4 dose-dependent cilia dysfunction.

Raveau M, Nakahari T, Asada S, Ishihara K, Amano K, Shimohata A, Sago H, Yamakawa K. Raveau M, et al. Among authors: ishihara k. Hum Mol Genet. 2017 Mar 1;26(5):923-931. doi: 10.1093/hmg/ddx007. Hum Mol Genet. 2017. PMID: 28069794

5

Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism.

Shimohata A, Ishihara K, Hattori S, Miyamoto H, Morishita H, Ornthanalai G, Raveau M, Ebrahim AS, Amano K, Yamada K, Sago H, Akiba S, Mataga N, Murphy NP, Miyakawa T, Yamakawa K. Shimohata A, et al. Among authors: ishihara k. Exp Neurol. 2017 Jul;293:1-12. doi: 10.1016/j.expneurol.2017.03.009. Epub 2017 Mar 20. Exp Neurol. 2017. PMID: 28336394

6

Copper accumulation in the brain causes the elevation of oxidative stress and less anxious behavior in Ts1Cje mice, a model of Down syndrome.

Ishihara K, Kawashita E, Shimizu R, Nagasawa K, Yasui H, Sago H, Yamakawa K, Akiba S. Ishihara K, et al. Free Radic Biol Med. 2019 Apr;134:248-259. doi: 10.1016/j.freeradbiomed.2019.01.015. Epub 2019 Jan 18. Free Radic Biol Med. 2019. PMID: 30660502

7

Perturbation of the immune cells and prenatal neurogenesis by the triplication of the Erg gene in mouse models of Down syndrome.

Ishihara K, Shimizu R, Takata K, Kawashita E, Amano K, Shimohata A, Low D, Nabe T, Sago H, Alexander WS, Ginhoux F, Yamakawa K, Akiba S. Ishihara K, et al. Brain Pathol. 2020 Jan;30(1):75-91. doi: 10.1111/bpa.12758. Epub 2019 Jul 4. Brain Pathol. 2020. PMID: 31206867 Free PMC article.

8

[Inhibition of Group IVA Phospholipase A₂ as a Novel Therapeutic Strategy for Nonalcoholic Steatohepatitis].

Akiba S, Kawashita E, Ishihara K. Akiba S, et al. Among authors: ishihara k. Yakugaku Zasshi. 2019;139(9):1155-1162. doi: 10.1248/yakushi.19-00011-2. Yakugaku Zasshi. 2019. PMID: 31474631 Free article. Japanese.

9

[Copper accumulation in the brain of Down syndrome model mice and its pathophysiological significance].

Ishihara K, Kawashita E, Akiba S. Ishihara K, et al. Nihon Yakurigaku Zasshi. 2019;154(6):335-339. doi: 10.1254/fpj.154.335. Nihon Yakurigaku Zasshi. 2019. PMID: 31787686 Review. Japanese.

10

Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.

Shimizu R, Ishihara K, Kawashita E, Sago H, Yamakawa K, Mizutani KI, Akiba S. Shimizu R, et al. Among authors: ishihara k. Biochem Biophys Res Commun. 2021 Jan 8;535:87-92. doi: 10.1016/j.bbrc.2020.12.026. Epub 2020 Dec 18. Biochem Biophys Res Commun. 2021. PMID: 33348080

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