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Short-term and longer-term protective immune responses generated by subunit vaccination with smallpox A33, B5, L1 or A27 proteins adjuvanted with aluminum hydroxide and CpG in mice challenged with vaccinia virus.
Xiao Y, Zeng Y, Schante C, Joshi SB, Buchman GW, Volkin DB, Middaugh CR, Isaacs SN. Xiao Y, et al. Among authors: isaacs sn. Vaccine. 2020 Aug 27;38(38):6007-6018. doi: 10.1016/j.vaccine.2020.07.018. Epub 2020 Jul 30. Vaccine. 2020. PMID: 32741672 Free PMC article.
Smallpox subunit vaccine produced in Planta confers protection in mice.
Golovkin M, Spitsin S, Andrianov V, Smirnov Y, Xiao Y, Pogrebnyak N, Markley K, Brodzik R, Gleba Y, Isaacs SN, Koprowski H. Golovkin M, et al. Among authors: isaacs sn. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6864-9. doi: 10.1073/pnas.0701451104. Epub 2007 Apr 11. Proc Natl Acad Sci U S A. 2007. PMID: 17428917 Free PMC article.
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