Isaacs RJ - Search Results

1

A model for initial DNA lesion recognition by NER and MMR based on local conformational flexibility.

Isaacs RJ, Spielmann HP. Isaacs RJ, et al. DNA Repair (Amst). 2004 May 4;3(5):455-64. doi: 10.1016/j.dnarep.2004.01.004. DNA Repair (Amst). 2004. PMID: 15162792 Review.

2

Structural differences in the NOE-derived structure of G-T mismatched DNA relative to normal DNA are correlated with differences in (13)C relaxation-based internal dynamics.

Isaacs RJ, Rayens WS, Spielmann HP. Isaacs RJ, et al. J Mol Biol. 2002 May 24;319(1):191-207. doi: 10.1016/S0022-2836(02)00265-6. J Mol Biol. 2002. PMID: 12051946

3

Insight into G[bond]T mismatch recognition using molecular dynamics with time-averaged restraints derived from NMR spectroscopy.

Isaacs RJ, Spielmann HP. Isaacs RJ, et al. J Am Chem Soc. 2004 Jan 21;126(2):583-90. doi: 10.1021/ja037333r. J Am Chem Soc. 2004. PMID: 14719957

4

Relationship of DNA structure to internal dynamics: correlation of helical parameters from NOE-based NMR solution structures of d(GCGTACGC)(2) and d(CGCTAGCG)(2) with (13)C order parameters implies conformational coupling in dinucleotide units.

Isaacs RJ, Spielmann HP. Isaacs RJ, et al. J Mol Biol. 2001 Mar 23;307(2):525-40. doi: 10.1006/jmbi.2001.4498. J Mol Biol. 2001. PMID: 11254380

5

NMR evidence for mechanical coupling of phosphate B(I)-B(II) transitions with deoxyribose conformational exchange in DNA.

Isaacs RJ, Spielmann HP. Isaacs RJ, et al. J Mol Biol. 2001 Aug 3;311(1):149-60. doi: 10.1006/jmbi.2001.4855. J Mol Biol. 2001. PMID: 11469864

6

Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase.

Chehade KA, Kiegiel K, Isaacs RJ, Pickett JS, Bowers KE, Fierke CA, Andres DA, Spielmann HP. Chehade KA, et al. Among authors: isaacs rj. J Am Chem Soc. 2002 Jul 17;124(28):8206-19. doi: 10.1021/ja0124717. J Am Chem Soc. 2002. PMID: 12105898

7

Protein farnesyltransferase isoprenoid substrate discrimination is dependent on isoprene double bonds and branched methyl groups.

Micali E, Chehade KA, Isaacs RJ, Andres DA, Spielmann HP. Micali E, et al. Among authors: isaacs rj. Biochemistry. 2001 Oct 16;40(41):12254-65. doi: 10.1021/bi011133f. Biochemistry. 2001. PMID: 11591144

8

How do I initiate and maintain a mobile apheresis service in the era of cellular therapy.

Karasick MH, Betancourt C, Dormesy S, Sheehy J, Isaacs RJ, Sachais BS, Shi PA. Karasick MH, et al. Among authors: isaacs rj. Transfusion. 2023 Jan;63(1):13-22. doi: 10.1111/trf.17143. Epub 2022 Oct 8. Transfusion. 2023. PMID: 36208142

9

Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents.

Fjellström O, Larsson N, Yasuda S, Tsuchida T, Oguma T, Marley A, Wennberg-Huldt C, Hovdal D, Fukuda H, Yoneyama Y, Sasaki K, Johansson A, Lundqvist S, Brengdahl J, Isaacs RJ, Brown D, Geschwindner S, Benthem L, Priest C, Turnbull A. Fjellström O, et al. Among authors: isaacs rj. PLoS One. 2015 Dec 31;10(12):e0145849. doi: 10.1371/journal.pone.0145849. eCollection 2015. PLoS One. 2015. PMID: 26720709 Free PMC article.

10

Characterization of the direct interaction between KcsA-Kv1.3 and its inhibitors.

Xu H, Hill JJ, Michelsen K, Yamane H, Kurzeja RJ, Tam T, Isaacs RJ, Shen F, Tagari P. Xu H, et al. Among authors: isaacs rj. Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):1974-80. doi: 10.1016/j.bbamem.2015.06.011. Epub 2015 Jun 12. Biochim Biophys Acta. 2015. PMID: 26074010 Free article.

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