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Genomically recoded organisms expand biological functions.
Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, Isaacs FJ. Lajoie MJ, et al. Among authors: isaacs fj. Science. 2013 Oct 18;342(6156):357-60. doi: 10.1126/science.1241459. Science. 2013. PMID: 24136966 Free PMC article.
Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.
Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB, Emig CJ, Bang D, Hwang SJ, Jewett MC, Jacobson JM, Church GM. Isaacs FJ, et al. Science. 2011 Jul 15;333(6040):348-53. doi: 10.1126/science.1205822. Science. 2011. PMID: 21764749 Free PMC article.
Designed phosphoprotein recognition in Escherichia coli.
Sawyer N, Gassaway BM, Haimovich AD, Isaacs FJ, Rinehart J, Regan L. Sawyer N, et al. Among authors: isaacs fj. ACS Chem Biol. 2014 Nov 21;9(11):2502-7. doi: 10.1021/cb500658w. Epub 2014 Oct 6. ACS Chem Biol. 2014. PMID: 25272187 Free PMC article.
67 results