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1,143 results

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C9orf72 repeat expansions modify risk for secondary motor and cognitive-behavioral symptoms in behavioral-variant frontotemporal degeneration and amyotrophic lateral sclerosis.
Spencer BE, Xie SX, Elman LB, Quinn CC, Amado D, Baer M, Lee EB, Van Deerlin V, Dratch L, Massimo L, Irwin DJ, McMillan CT. Spencer BE, et al. Among authors: irwin dj. medRxiv [Preprint]. 2024 May 1:2024.04.30.24306638. doi: 10.1101/2024.04.30.24306638. medRxiv. 2024. PMID: 38746326 Free PMC article. Preprint.
Progranulin AAV gene therapy for frontotemporal dementia: translational studies and phase 1/2 trial interim results.
Sevigny J, Uspenskaya O, Heckman LD, Wong LC, Hatch DA, Tewari A, Vandenberghe R, Irwin DJ, Saracino D, Le Ber I, Ahmed R, Rohrer JD, Boxer AL, Boland S, Sheehan P, Brandes A, Burstein SR, Shykind BM, Kamalakaran S, Daniels CW, David Litwack E, Mahoney E, Velaga J, McNamara I, Sondergaard P, Sajjad SA, Kobayashi YM, Abeliovich A, Hefti F. Sevigny J, et al. Among authors: irwin dj. Nat Med. 2024 May 14. doi: 10.1038/s41591-024-02973-0. Online ahead of print. Nat Med. 2024. PMID: 38745011
A Single-center Experience with a Shear Thinning Conformable Embolic.
Pal K, Patel M, Chen SR, Odisio B, Metwalli Z, Ahrar J, Irwin D, Sheth RA, Kuban JD. Pal K, et al. Among authors: irwin d. J Vasc Interv Radiol. 2024 May 6:S1051-0443(24)00327-0. doi: 10.1016/j.jvir.2024.04.024. Online ahead of print. J Vasc Interv Radiol. 2024. PMID: 38719091 Free article.
Pathologic and cognitive correlates of plasma biomarkers in neurodegenerative disease.
Cousins KAQ, Phillips JS, Das SR, O'Brien K, Tropea TF, Chen-Plotkin A, Shaw LM, Nasrallah IM, Mechanic-Hamilton D, McMillan CT, Irwin DJ, Lee EB, Wolk DA. Cousins KAQ, et al. Among authors: irwin dj. Alzheimers Dement. 2024 Apr 21. doi: 10.1002/alz.13777. Online ahead of print. Alzheimers Dement. 2024. PMID: 38644682
Gene specific effects on brain volume and cognition of TMEM106B in frontotemporal lobar degeneration.
Vandebergh M, Ramos EM, Corriveau-Lecavalier N, Ramanan VK, Kornak J, Mester C, Kolander T, Brushaber D, Staffaroni AM, Geschwind D, Wolf A, Kantarci K, Gendron TF, Petrucelli L, Van den Broeck M, Wynants S, Baker MC, Borrego-Écija S, Appleby B, Barmada S, Bozoki A, Clark D, Darby RR, Dickerson BC, Domoto-Reilly K, Fields JA, Galasko DR, Ghoshal N, Graff-Radford N, Grant IM, Honig LS, Hsiung GR, Huey ED, Irwin D, Knopman DS, Kwan JY, Léger GC, Litvan I, Masdeu JC, Mendez MF, Onyike C, Pascual B, Pressman P, Ritter A, Roberson ED, Snyder A, Sullivan AC, Tartaglia MC, Wint D, Heuer HW, Forsberg LK, Boxer AL, Rosen HJ, Boeve BF, Rademakers R. Vandebergh M, et al. Among authors: irwin d. medRxiv [Preprint]. 2024 Apr 5:2024.04.05.24305253. doi: 10.1101/2024.04.05.24305253. medRxiv. 2024. PMID: 38633784 Free PMC article. Preprint.
MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study.
Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, Christopher EA, DeTure M, Seeley WW, Lee EB, Frosch MP, Molina-Porcel L, Gefen T, Redding-Ochoa J, Ghetti B, Robinson AC, Kobylecki C, Rowe JB, Beach TG, Teich AF, Keith JL, Bodi I, Halliday GM, Gearing M, Arzberger T, Morris CM, White CL 3rd, Mechawar N, Boluda S, MacKenzie IR, McLean C, Cykowski MD, Wang SJ, Graff C, Nagra RM, Kovacs GG, Giaccone G, Neumann M, Ang LC, Carvalho A, Morris HR, Rademakers R, Hardy JA, Dickson DW, Rohrer JD, Ross OA; Pick's disease International Consortium. Valentino RR, et al. Lancet Neurol. 2024 May;23(5):487-499. doi: 10.1016/S1474-4422(24)00083-8. Lancet Neurol. 2024. PMID: 38631765 Free article.
Greater white matter degeneration and lower structural connectivity in non-amnestic vs. amnestic Alzheimer's disease.
Phillips JS, Adluru N, Chung MK, Radhakrishnan H, Olm CA, Cook PA, Gee JC, Cousins KAQ, Arezoumandan S, Wolk DA, McMillan CT, Grossman M, Irwin DJ. Phillips JS, et al. Among authors: irwin dj. Front Neurosci. 2024 Mar 18;18:1353306. doi: 10.3389/fnins.2024.1353306. eCollection 2024. Front Neurosci. 2024. PMID: 38567286 Free PMC article.
1,143 results