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Cardiac myosin filaments are directly regulated by calcium.
Ma W, Nag S, Gong H, Qi L, Irving TC. Ma W, et al. Among authors: irving tc. J Gen Physiol. 2022 Dec 5;154(12):e202213213. doi: 10.1085/jgp.202213213. Epub 2022 Nov 1. J Gen Physiol. 2022. PMID: 36327149 Free PMC article.
Reverse actin sliding triggers strong myosin binding that moves tropomyosin.
Bekyarova TI, Reedy MC, Baumann BA, Tregear RT, Ward A, Krzic U, Prince KM, Perz-Edwards RJ, Reconditi M, Gore D, Irving TC, Reedy MK. Bekyarova TI, et al. Among authors: irving tc. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10372-7. doi: 10.1073/pnas.0709877105. Epub 2008 Jul 25. Proc Natl Acad Sci U S A. 2008. PMID: 18658238 Free PMC article.
Elastic proteins in the flight muscle of Manduca sexta.
Yuan CC, Ma W, Schemmel P, Cheng YS, Liu J, Tsaprailis G, Feldman S, Ayme Southgate A, Irving TC. Yuan CC, et al. Among authors: irving tc. Arch Biochem Biophys. 2015 Feb 15;568:16-27. doi: 10.1016/j.abb.2014.12.033. Epub 2015 Jan 17. Arch Biochem Biophys. 2015. PMID: 25602701 Free PMC article.
Hypercontractile mutant of ventricular myosin essential light chain leads to disruption of sarcomeric structure and function and results in restrictive cardiomyopathy in mice.
Yuan CC, Kazmierczak K, Liang J, Kanashiro-Takeuchi R, Irving TC, Gomes AV, Wang Y, Burghardt TP, Szczesna-Cordary D. Yuan CC, et al. Among authors: irving tc. Cardiovasc Res. 2017 Aug 1;113(10):1124-1136. doi: 10.1093/cvr/cvx060. Cardiovasc Res. 2017. PMID: 28371863 Free PMC article.
Dysfunctional sarcomere contractility contributes to muscle weakness in ACTA1-related nemaline myopathy (NEM3).
Joureau B, de Winter JM, Conijn S, Bogaards SJP, Kovacevic I, Kalganov A, Persson M, Lindqvist J, Stienen GJM, Irving TC, Ma W, Yuen M, Clarke NF, Rassier DE, Malfatti E, Romero NB, Beggs AH, Ottenheijm CAC. Joureau B, et al. Among authors: irving tc. Ann Neurol. 2018 Feb;83(2):269-282. doi: 10.1002/ana.25144. Epub 2018 Feb 6. Ann Neurol. 2018. PMID: 29328520 Free PMC article.
176 results