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Osteal macrophages support osteoclast-mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model.
Batoon L, Millard SM, Raggatt LJ, Wu AC, Kaur S, Sun LWH, Williams K, Sandrock C, Ng PY, Irvine KM, Bartnikowski M, Glatt V, Pavlos NJ, Pettit AR. Batoon L, et al. Among authors: irvine km. J Bone Miner Res. 2021 Nov;36(11):2214-2228. doi: 10.1002/jbmr.4413. Epub 2021 Aug 3. J Bone Miner Res. 2021. PMID: 34278602 Free article.
A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System.
Grabert K, Sehgal A, Irvine KM, Wollscheid-Lengeling E, Ozdemir DD, Stables J, Luke GA, Ryan MD, Adamson A, Humphreys NE, Sandrock CJ, Rojo R, Verkasalo VA, Mueller W, Hohenstein P, Pettit AR, Pridans C, Hume DA. Grabert K, et al. Among authors: irvine km. J Immunol. 2020 Dec 1;205(11):3154-3166. doi: 10.4049/jimmunol.2000835. Epub 2020 Nov 2. J Immunol. 2020. PMID: 33139489
CSF1R-dependent macrophages control postnatal somatic growth and organ maturation.
Keshvari S, Caruso M, Teakle N, Batoon L, Sehgal A, Patkar OL, Ferrari-Cestari M, Snell CE, Chen C, Stevenson A, Davis FM, Bush SJ, Pridans C, Summers KM, Pettit AR, Irvine KM, Hume DA. Keshvari S, et al. Among authors: irvine km. PLoS Genet. 2021 Jun 3;17(6):e1009605. doi: 10.1371/journal.pgen.1009605. eCollection 2021 Jun. PLoS Genet. 2021. PMID: 34081701 Free PMC article.
Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues.
Millard SM, Heng O, Opperman KS, Sehgal A, Irvine KM, Kaur S, Sandrock CJ, Wu AC, Magor GW, Batoon L, Perkins AC, Noll JE, Zannettino ACW, Sester DP, Levesque JP, Hume DA, Raggatt LJ, Summers KM, Pettit AR. Millard SM, et al. Among authors: irvine km. Cell Rep. 2021 Nov 23;37(8):110058. doi: 10.1016/j.celrep.2021.110058. Cell Rep. 2021. PMID: 34818538 Free article.
Therapeutic potential of macrophage colony-stimulating factor in chronic liver disease.
Keshvari S, Genz B, Teakle N, Caruso M, Cestari MF, Patkar OL, Tse BWC, Sokolowski KA, Ebersbach H, Jascur J, MacDonald KPA, Miller G, Ramm GA, Pettit AR, Clouston AD, Powell EE, Hume DA, Irvine KM. Keshvari S, et al. Among authors: irvine km. Dis Model Mech. 2022 Apr 1;15(4):dmm049387. doi: 10.1242/dmm.049387. Epub 2022 Apr 19. Dis Model Mech. 2022. PMID: 35169835 Free PMC article.
Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism.
Keshvari S, Masson JJR, Ferrari-Cestari M, Bodea LG, Nooru-Mohamed F, Tse BWC, Sokolowski KA, Batoon L, Patkar OL, Sullivan MA, Ebersbach H, Stutz C, Parton RG, Summers KM, Pettit AR, Hume DA, Irvine KM. Keshvari S, et al. Among authors: irvine km. Am J Physiol Endocrinol Metab. 2024 Feb 1;326(2):E149-E165. doi: 10.1152/ajpendo.00347.2023. Epub 2023 Dec 20. Am J Physiol Endocrinol Metab. 2024. PMID: 38117267
126 results