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Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses.
Jeyachandran AV, Irudayam JI, Dubey S, Chakravarty N, Konda B, Shah A, Su B, Wang C, Cui Q, Williams KJ, Srikanth S, Shi Y, Deb A, Damoiseaux R, Stripp BR, Ramaiah A, Arumugaswami V. Jeyachandran AV, et al. Among authors: irudayam ji. bioRxiv [Preprint]. 2023 Aug 5:2023.08.04.552083. doi: 10.1101/2023.08.04.552083. bioRxiv. 2023. PMID: 37577539 Free PMC article. Preprint.
Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses.
Garcia G Jr, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Castillo Cario S, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells MS, Ramaiah A, Arumugaswami V. Garcia G Jr, et al. Among authors: irudayam ji. Cell Rep Med. 2023 May 16;4(5):101024. doi: 10.1016/j.xcrm.2023.101024. Epub 2023 Apr 28. Cell Rep Med. 2023. PMID: 37119814 Free PMC article.
Broad-spectrum antiviral inhibitors targeting pandemic potential RNA viruses.
Garcia G Jr, Irudayam JI, Jeyachandran AV, Dubey S, Chang C, Cario SC, Price N, Arumugam S, Marquez AL, Shah A, Fanaei A, Chakravarty N, Joshi S, Sinha S, French SW, Parcells M, Ramaiah A, Arumugaswami V. Garcia G Jr, et al. Among authors: irudayam ji. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524824. doi: 10.1101/2023.01.19.524824. bioRxiv. 2023. PMID: 36711787 Free PMC article. Updated. Preprint.
Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response.
Garcia G Jr, Jeyachandran AV, Wang Y, Irudayam JI, Cario SC, Sen C, Li S, Li Y, Kumar A, Nielsen-Saines K, French SW, Shah PS, Morizono K, Gomperts BN, Deb A, Ramaiah A, Arumugaswami V. Garcia G Jr, et al. Among authors: irudayam ji. PLoS Biol. 2022 Nov 8;20(11):e3001851. doi: 10.1371/journal.pbio.3001851. eCollection 2022 Nov. PLoS Biol. 2022. PMID: 36346780 Free PMC article.
Characterization of type I interferon pathway during hepatic differentiation of human pluripotent stem cells and hepatitis C virus infection.
Irudayam JI, Contreras D, Spurka L, Subramanian A, Allen J, Ren S, Kanagavel V, Nguyen Q, Ramaiah A, Ramamoorthy K, French SW, Klein AS, Funari V, Arumugaswami V. Irudayam JI, et al. Stem Cell Res. 2015 Sep;15(2):354-364. doi: 10.1016/j.scr.2015.08.003. Epub 2015 Aug 15. Stem Cell Res. 2015. PMID: 26313525 Free PMC article.