Irth H - Search Results

1

Biosensor discovery of thyroxine transport disrupting chemicals.

Marchesini GR, Meimaridou A, Haasnoot W, Meulenberg E, Albertus F, Mizuguchi M, Takeuchi M, Irth H, Murk AJ. Marchesini GR, et al. Among authors: irth h. Toxicol Appl Pharmacol. 2008 Oct 1;232(1):150-60. doi: 10.1016/j.taap.2008.06.014. Epub 2008 Jul 2. Toxicol Appl Pharmacol. 2008. PMID: 18647617

2

Spreeta-based biosensor assays for endocrine disruptors.

Marchesini GR, Koopal K, Meulenberg E, Haasnoot W, Irth H. Marchesini GR, et al. Among authors: irth h. Biosens Bioelectron. 2007 Apr 15;22(9-10):1908-15. doi: 10.1016/j.bios.2006.08.005. Epub 2006 Sep 12. Biosens Bioelectron. 2007. PMID: 16971108

3

Biosensor recognition of thyroid-disrupting chemicals using transport proteins.

Marchesini GR, Meulenberg E, Haasnoot W, Mizuguchi M, Irth H. Marchesini GR, et al. Among authors: irth h. Anal Chem. 2006 Feb 15;78(4):1107-14. doi: 10.1021/ac051399i. Anal Chem. 2006. PMID: 16478101

4

Metabolic profiling of endocrine-disrupting compounds by on-line cytochrome p450 bioreaction coupled to on-line receptor affinity screening.

Van Liempd SM, Kool J, Meerman JH, Irth H, Vermeulen NP. Van Liempd SM, et al. Among authors: irth h. Chem Res Toxicol. 2007 Dec;20(12):1825-32. doi: 10.1021/tx7000724. Epub 2007 Nov 1. Chem Res Toxicol. 2007. PMID: 17975887

5

Development of surface plasmon resonance biosensor assays for primary and secondary screening of acetylcholine binding protein ligands.

Retra K, Geitmann M, Kool J, Smit AB, de Esch IJ, Danielson UH, Irth H. Retra K, et al. Among authors: irth h. Anal Biochem. 2010 Dec 1;407(1):58-64. doi: 10.1016/j.ab.2010.06.021. Epub 2010 Jun 17. Anal Biochem. 2010. PMID: 20599657

6

Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands.

de Kloe GE, Retra K, Geitmann M, Källblad P, Nahar T, van Elk R, Smit AB, van Muijlwijk-Koezen JE, Leurs R, Irth H, Danielson UH, de Esch IJ. de Kloe GE, et al. Among authors: irth h. J Med Chem. 2010 Oct 14;53(19):7192-201. doi: 10.1021/jm100834y. J Med Chem. 2010. PMID: 20828128

7

Target immobilization as a strategy for NMR-based fragment screening: comparison of TINS, STD, and SPR for fragment hit identification.

Kobayashi M, Retra K, Figaroa F, Hollander JG, Ab E, Heetebrij RJ, Irth H, Siegal G. Kobayashi M, et al. Among authors: irth h. J Biomol Screen. 2010 Sep;15(8):978-89. doi: 10.1177/1087057110375614. J Biomol Screen. 2010. PMID: 20817886

8

Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR.

de Vlieger JS, Kolkman AJ, Ampt KA, Commandeur JN, Vermeulen NP, Kool J, Wijmenga SS, Niessen WM, Irth H, Honing M. de Vlieger JS, et al. Among authors: irth h. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Mar 1;878(7-8):667-74. doi: 10.1016/j.jchromb.2010.01.035. Epub 2010 Jan 29. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 20149764

9

High resolution screening of plant natural product extracts for estrogen receptor alpha and beta binding activity using an online HPLC-MS biochemical detection system.

Schobel U, Frenay M, van Elswijk DA, McAndrews JM, Long KR, Olson LM, Bobzin SC, Irth H. Schobel U, et al. Among authors: irth h. J Biomol Screen. 2001 Oct;6(5):291-303. doi: 10.1177/108705710100600503. J Biomol Screen. 2001. PMID: 11689129

10

Rapid on-line profiling of estrogen receptor binding metabolites of tamoxifen.

Kool J, Ramautar R, van Liempd SM, Beckman J, de Kanter FJ, Meerman JH, Schenk T, Irth H, Commandeur JN, Vermeulen NP. Kool J, et al. Among authors: irth h. J Med Chem. 2006 Jun 1;49(11):3287-92. doi: 10.1021/jm0507936. J Med Chem. 2006. PMID: 16722647

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