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Glioma cells require one-carbon metabolism to survive glutamine starvation.
Tanaka K, Sasayama T, Nagashima H, Irino Y, Takahashi M, Izumi Y, Uno T, Satoh N, Kitta A, Kyotani K, Fujita Y, Hashiguchi M, Nakai T, Kohta M, Uozumi Y, Shinohara M, Hosoda K, Bamba T, Kohmura E. Tanaka K, et al. Among authors: irino y. Acta Neuropathol Commun. 2021 Jan 19;9(1):16. doi: 10.1186/s40478-020-01114-1. Acta Neuropathol Commun. 2021. PMID: 33468252 Free PMC article.
GC/MS-based metabolomic analysis of cerebrospinal fluid (CSF) from glioma patients.
Nakamizo S, Sasayama T, Shinohara M, Irino Y, Nishiumi S, Nishihara M, Tanaka H, Tanaka K, Mizukawa K, Itoh T, Taniguchi M, Hosoda K, Yoshida M, Kohmura E. Nakamizo S, et al. Among authors: irino y. J Neurooncol. 2013 May;113(1):65-74. doi: 10.1007/s11060-013-1090-x. Epub 2013 Mar 1. J Neurooncol. 2013. PMID: 23456655 Free PMC article.
Pentose phosphate pathway activation via HSP27 phosphorylation by ATM kinase: A putative endogenous antioxidant defense mechanism during cerebral ischemia-reperfusion.
Yamamoto Y, Hosoda K, Imahori T, Tanaka J, Matsuo K, Nakai T, Irino Y, Shinohara M, Sato N, Sasayama T, Tanaka K, Nagashima H, Kohta M, Kohmura E. Yamamoto Y, et al. Among authors: irino y. Brain Res. 2018 May 15;1687:82-94. doi: 10.1016/j.brainres.2018.03.001. Epub 2018 Mar 3. Brain Res. 2018. PMID: 29510140
Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment.
Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H, Satoh N, Kyotani K, Mizowaki T, Imahori T, Ejima Y, Masui K, Gini B, Yang H, Hosoda K, Sasaki R, Mischel PS, Kohmura E. Tanaka K, et al. Among authors: irino y. J Clin Invest. 2015 Apr;125(4):1591-602. doi: 10.1172/JCI78239. Epub 2015 Mar 23. J Clin Invest. 2015. PMID: 25798620 Free PMC article.
Corrigendum to "Combined metabolic and transcriptional profiling identifies pentose phosphate pathway activation by HSP27 phosphorylation during cerebral ischemia" [Neuroscience 349 (2017) 1-16].
Imahori T, Hosoda K, Nakai T, Yamamoto Y, Irino Y, Shinohara M, Sato N, Sasayama T, Tanaka K, Nagashima H, Kohta M, Kohmura E. Imahori T, et al. Among authors: irino y. Neuroscience. 2017 Aug 15;357:414. doi: 10.1016/j.neuroscience.2017.04.018. Epub 2017 Apr 25. Neuroscience. 2017. PMID: 28450085 No abstract available.
Critical role of glutamine metabolism in cardiomyocytes under oxidative stress.
Watanabe K, Nagao M, Toh R, Irino Y, Shinohara M, Iino T, Yoshikawa S, Tanaka H, Satomi-Kobayashi S, Ishida T, Hirata KI. Watanabe K, et al. Among authors: irino y. Biochem Biophys Res Commun. 2021 Jan 1;534:687-693. doi: 10.1016/j.bbrc.2020.11.018. Epub 2020 Nov 17. Biochem Biophys Res Commun. 2021. PMID: 33213841
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