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A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing.
Angiolini F, Belloni E, Giordano M, Campioni M, Forneris F, Paronetto MP, Lupia M, Brandas C, Pradella D, Di Matteo A, Giampietro C, Jodice G, Luise C, Bertalot G, Freddi S, Malinverno M, Irimia M, Moulton JD, Summerton J, Chiapparino A, Ghilardi C, Giavazzi R, Nyqvist D, Gabellini D, Dejana E, Cavallaro U, Ghigna C. Angiolini F, et al. Among authors: irimia m. Elife. 2019 Mar 4;8:e44305. doi: 10.7554/eLife.44305. Elife. 2019. PMID: 30829570 Free PMC article.
Parallel evolution of amphioxus and vertebrate small-scale gene duplications.
Brasó-Vives M, Marlétaz F, Echchiki A, Mantica F, Acemel RD, Gómez-Skarmeta JL, Hartasánchez DA, Le Targa L, Pontarotti P, Tena JJ, Maeso I, Escriva H, Irimia M, Robinson-Rechavi M. Brasó-Vives M, et al. Among authors: irimia m. Genome Biol. 2022 Nov 18;23(1):243. doi: 10.1186/s13059-022-02808-6. Genome Biol. 2022. PMID: 36401278 Free PMC article.
The alternative splicing factor Nova2 regulates vascular development and lumen formation.
Giampietro C, Deflorian G, Gallo S, Di Matteo A, Pradella D, Bonomi S, Belloni E, Nyqvist D, Quaranta V, Confalonieri S, Bertalot G, Orsenigo F, Pisati F, Ferrero E, Biamonti G, Fredrickx E, Taveggia C, Wyatt CD, Irimia M, Di Fiore PP, Blencowe BJ, Dejana E, Ghigna C. Giampietro C, et al. Among authors: irimia m. Nat Commun. 2015 Oct 8;6:8479. doi: 10.1038/ncomms9479. Nat Commun. 2015. PMID: 26446569 Free PMC article.
An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms.
Tapial J, Ha KCH, Sterne-Weiler T, Gohr A, Braunschweig U, Hermoso-Pulido A, Quesnel-Vallières M, Permanyer J, Sodaei R, Marquez Y, Cozzuto L, Wang X, Gómez-Velázquez M, Rayon T, Manzanares M, Ponomarenko J, Blencowe BJ, Irimia M. Tapial J, et al. Among authors: irimia m. Genome Res. 2017 Oct;27(10):1759-1768. doi: 10.1101/gr.220962.117. Epub 2017 Aug 30. Genome Res. 2017. PMID: 28855263 Free PMC article.
Matt: Unix tools for alternative splicing analysis.
Gohr A, Irimia M. Gohr A, et al. Among authors: irimia m. Bioinformatics. 2019 Jan 1;35(1):130-132. doi: 10.1093/bioinformatics/bty606. Bioinformatics. 2019. PMID: 30010778
A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons.
Torres-Méndez A, Bonnal S, Marquez Y, Roth J, Iglesias M, Permanyer J, Almudí I, O'Hanlon D, Guitart T, Soller M, Gingras AC, Gebauer F, Rentzsch F, Blencowe BJ, Valcárcel J, Irimia M. Torres-Méndez A, et al. Among authors: irimia m. Nat Ecol Evol. 2019 Apr;3(4):691-701. doi: 10.1038/s41559-019-0813-6. Epub 2019 Mar 4. Nat Ecol Evol. 2019. PMID: 30833759
147 results