Irie S - Search Results

1

Microdosing clinical study: pharmacokinetic, pharmacogenomic (SLCO2B1), and interaction (grapefruit juice) profiles of celiprolol following the oral microdose and therapeutic dose.

Ieiri I, Doi Y, Maeda K, Sasaki T, Kimura M, Hirota T, Chiyoda T, Miyagawa M, Irie S, Iwasaki K, Sugiyama Y. Ieiri I, et al. Among authors: irie s. J Clin Pharmacol. 2012 Jul;52(7):1078-89. doi: 10.1177/0091270011408612. Epub 2011 May 18. J Clin Pharmacol. 2012. PMID: 21593283 Clinical Trial.

2

Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

Kurata Y, Ieiri I, Kimura M, Morita T, Irie S, Urae A, Ohdo S, Ohtani H, Sawada Y, Higuchi S, Otsubo K. Kurata Y, et al. Among authors: irie s. Clin Pharmacol Ther. 2002 Aug;72(2):209-19. doi: 10.1067/mcp.2002.126177. Clin Pharmacol Ther. 2002. PMID: 12189368

3

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics.

Nishizato Y, Ieiri I, Suzuki H, Kimura M, Kawabata K, Hirota T, Takane H, Irie S, Kusuhara H, Urasaki Y, Urae A, Higuchi S, Otsubo K, Sugiyama Y. Nishizato Y, et al. Among authors: irie s. Clin Pharmacol Ther. 2003 Jun;73(6):554-65. doi: 10.1016/S0009-9236(03)00060-2. Clin Pharmacol Ther. 2003. PMID: 12811365

4

Pharmacokinetic interaction between pravastatin and olmesartan in relation to SLCO1B1 polymorphism.

Suwannakul S, Ieiri I, Kimura M, Kawabata K, Kusuhara H, Hirota T, Irie S, Sugiyama Y, Higuchi S. Suwannakul S, et al. Among authors: irie s. J Hum Genet. 2008;53(10):899-904. doi: 10.1007/s10038-008-0324-9. Epub 2008 Jul 19. J Hum Genet. 2008. PMID: 18641915

5

Pharmacokinetic and pharmacogenomic profiles of telmisartan after the oral microdose and therapeutic dose.

Ieiri I, Nishimura C, Maeda K, Sasaki T, Kimura M, Chiyoda T, Hirota T, Irie S, Shimizu H, Noguchi T, Yoshida K, Sugiyama Y. Ieiri I, et al. Among authors: irie s. Pharmacogenet Genomics. 2011 Aug;21(8):495-505. doi: 10.1097/FPC.0b013e3283489ce2. Pharmacogenet Genomics. 2011. PMID: 21691256 Clinical Trial.

6

Pharmacogenomic/pharmacokinetic assessment of a four-probe cocktail for CYPs and OATPs following oral microdosing.

Ieiri I, Fukae M, Maeda K, Ando Y, Kimura M, Hirota T, Nakamura T, Iwasaki K, Matsuki S, Matsuguma K, Kanda E, Deguchi M, Irie S, Sugiyama Y. Ieiri I, et al. Among authors: irie s. Int J Clin Pharmacol Ther. 2012 Oct;50(10):689-700. doi: 10.5414/CP201763. Int J Clin Pharmacol Ther. 2012. PMID: 22853867

7

Mechanisms of pharmacokinetic enhancement between ritonavir and saquinavir; micro/small dosing tests using midazolam (CYP3A4), fexofenadine (p-glycoprotein), and pravastatin (OATP1B1) as probe drugs.

Ieiri I, Tsunemitsu S, Maeda K, Ando Y, Izumi N, Kimura M, Yamane N, Okuzono T, Morishita M, Kotani N, Kanda E, Deguchi M, Matsuguma K, Matsuki S, Hirota T, Irie S, Kusuhara H, Sugiyama Y. Ieiri I, et al. Among authors: irie s. J Clin Pharmacol. 2013 Jun;53(6):654-61. doi: 10.1002/jcph.62. Epub 2013 Feb 4. J Clin Pharmacol. 2013. PMID: 23381882 Clinical Trial.

8

Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP.

Kashihara Y, Ieiri I, Yoshikado T, Maeda K, Fukae M, Kimura M, Hirota T, Matsuki S, Irie S, Izumi N, Kusuhara H, Sugiyama Y. Kashihara Y, et al. Among authors: irie s. J Pharm Sci. 2017 Sep;106(9):2688-2694. doi: 10.1016/j.xphs.2017.03.010. Epub 2017 Mar 18. J Pharm Sci. 2017. PMID: 28322941

9

Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation.

Kashihara Y, Terao Y, Yoda K, Hirota T, Kubota T, Kimura M, Matsuki S, Hirakawa M, Irie S, Ieiri I. Kashihara Y, et al. Among authors: irie s. Eur J Clin Pharmacol. 2019 Mar;75(3):351-361. doi: 10.1007/s00228-018-2568-4. Epub 2018 Oct 31. Eur J Clin Pharmacol. 2019. PMID: 30382297 Clinical Trial.

10

Effects of dosing interval on the pharmacokinetic interaction between oral small spherical activated charcoal and amlodipine in humans.

Tanaka C, Ohtani H, Tsujimoto M, Ohdo S, Taniguchi M, Mizooku Y, Saitoh Y, Kimura M, Uchimaru H, Irie S, Sawada Y. Tanaka C, et al. Among authors: irie s. J Clin Pharmacol. 2007 Jul;47(7):904-8. doi: 10.1177/0091270007301622. J Clin Pharmacol. 2007. PMID: 17585118 No abstract available.

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