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Page 1
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer.
Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, Madhu B, Goldgraben MA, Caldwell ME, Allard D, Frese KK, Denicola G, Feig C, Combs C, Winter SP, Ireland-Zecchini H, Reichelt S, Howat WJ, Chang A, Dhara M, Wang L, Rückert F, Grützmann R, Pilarsky C, Izeradjene K, Hingorani SR, Huang P, Davies SE, Plunkett W, Egorin M, Hruban RH, Whitebread N, McGovern K, Adams J, Iacobuzio-Donahue C, Griffiths J, Tuveson DA. Olive KP, et al. Among authors: ireland zecchini h. Science. 2009 Jun 12;324(5933):1457-61. doi: 10.1126/science.1171362. Epub 2009 May 21. Science. 2009. PMID: 19460966 Free PMC article.
Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer.
Zecchini V, Madhu B, Russell R, Pértega-Gomes N, Warren A, Gaude E, Borlido J, Stark R, Ireland-Zecchini H, Rao R, Scott H, Boren J, Massie C, Asim M, Brindle K, Griffiths J, Frezza C, Neal DE, Mills IG. Zecchini V, et al. Among authors: ireland zecchini h. EMBO J. 2014 Jun 17;33(12):1365-82. doi: 10.15252/embj.201386874. Epub 2014 May 16. EMBO J. 2014. PMID: 24837709 Free PMC article.
Imaging sialylated tumor cell glycans in vivo.
Neves AA, Stöckmann H, Harmston RR, Pryor HJ, Alam IS, Ireland-Zecchini H, Lewis DY, Lyons SK, Leeper FJ, Brindle KM. Neves AA, et al. Among authors: ireland zecchini h. FASEB J. 2011 Aug;25(8):2528-37. doi: 10.1096/fj.10-178590. Epub 2011 Apr 14. FASEB J. 2011. PMID: 21493886
Dual-sugar imaging using isonitrile and azido-based click chemistries.
Wainman YA, Neves AA, Stairs S, Stöckmann H, Ireland-Zecchini H, Brindle KM, Leeper FJ. Wainman YA, et al. Among authors: ireland zecchini h. Org Biomol Chem. 2013 Nov 14;11(42):7297-300. doi: 10.1039/c3ob41805g. Org Biomol Chem. 2013. PMID: 24065211 Free PMC article.
Metabolic glycan imaging by isonitrile-tetrazine click chemistry.
Stairs S, Neves AA, Stöckmann H, Wainman YA, Ireland-Zecchini H, Brindle KM, Leeper FJ. Stairs S, et al. Among authors: ireland zecchini h. Chembiochem. 2013 Jun 17;14(9):1063-7. doi: 10.1002/cbic.201300130. Epub 2013 May 13. Chembiochem. 2013. PMID: 23670994 Free PMC article.