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Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy.
Marsili G, Acchioni C, Remoli AL, Amatore D, Sgarbanti R, De Angelis M, Orsatti R, Acchioni M, Astolfi A, Iraci N, Puzelli S, Facchini M, Perrotti E, Cecchetti V, Sabatini S, Superti F, Agamennone M, Barreca ML, Hiscott J, Nencioni L, Sgarbanti M. Marsili G, et al. Among authors: iraci n. Int J Mol Sci. 2023 Jun 22;24(13):10495. doi: 10.3390/ijms241310495. Int J Mol Sci. 2023. PMID: 37445672 Free PMC article.
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators.
Bertamino A, Ostacolo C, Ambrosino P, Musella S, Di Sarno V, Ciaglia T, Soldovieri MV, Iraci N, Fernandez Carvajal A, de la Torre-Martinez R, Ferrer-Montiel A, Gonzalez Muniz R, Novellino E, Taglialatela M, Campiglia P, Gomez-Monterrey I. Bertamino A, et al. Among authors: iraci n. J Med Chem. 2016 Mar 10;59(5):2179-91. doi: 10.1021/acs.jmedchem.5b01914. Epub 2016 Feb 17. J Med Chem. 2016. PMID: 26847872 Free article.
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators.
Ostacolo C, Miceli F, Di Sarno V, Nappi P, Iraci N, Soldovieri MV, Ciaglia T, Ambrosino P, Vestuto V, Lauritano A, Musella S, Pepe G, Basilicata MG, Manfra M, Perinelli DR, Novellino E, Bertamino A, Gomez-Monterrey IM, Campiglia P, Taglialatela M. Ostacolo C, et al. Among authors: iraci n. J Med Chem. 2020 Jan 9;63(1):163-185. doi: 10.1021/acs.jmedchem.9b00796. Epub 2019 Dec 24. J Med Chem. 2020. PMID: 31815462
ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.
Henderson MJ, Haber M, Porro A, Munoz MA, Iraci N, Xue C, Murray J, Flemming CL, Smith J, Fletcher JI, Gherardi S, Kwek CK, Russell AJ, Valli E, London WB, Buxton AB, Ashton LJ, Sartorelli AC, Cohn SL, Schwab M, Marshall GM, Perini G, Norris MD. Henderson MJ, et al. Among authors: iraci n. J Natl Cancer Inst. 2011 Aug 17;103(16):1236-51. doi: 10.1093/jnci/djr256. Epub 2011 Jul 28. J Natl Cancer Inst. 2011. PMID: 21799180 Free PMC article.
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis.
Liu T, Tee AE, Porro A, Smith SA, Dwarte T, Liu PY, Iraci N, Sekyere E, Haber M, Norris MD, Diolaiti D, Della Valle G, Perini G, Marshall GM. Liu T, et al. Among authors: iraci n. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18682-7. doi: 10.1073/pnas.0705524104. Epub 2007 Nov 14. Proc Natl Acad Sci U S A. 2007. PMID: 18003922 Free PMC article.
p53 is a direct transcriptional target of MYCN in neuroblastoma.
Chen L, Iraci N, Gherardi S, Gamble LD, Wood KM, Perini G, Lunec J, Tweddle DA. Chen L, et al. Among authors: iraci n. Cancer Res. 2010 Feb 15;70(4):1377-88. doi: 10.1158/0008-5472.CAN-09-2598. Epub 2010 Feb 9. Cancer Res. 2010. PMID: 20145147 Free PMC article.
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells.
Porro A, Haber M, Diolaiti D, Iraci N, Henderson M, Gherardi S, Valli E, Munoz MA, Xue C, Flemming C, Schwab M, Wong JH, Marshall GM, Della Valle G, Norris MD, Perini G. Porro A, et al. Among authors: iraci n. J Biol Chem. 2010 Jun 18;285(25):19532-43. doi: 10.1074/jbc.M109.078584. Epub 2010 Mar 16. J Biol Chem. 2010. PMID: 20233711 Free PMC article.
c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in chronic myelogenous leukemia CD34+ hematopoietic progenitor cells.
Porro A, Iraci N, Soverini S, Diolaiti D, Gherardi S, Terragna C, Durante S, Valli E, Kalebic T, Bernardoni R, Perrod C, Haber M, Norris MD, Baccarani M, Martinelli G, Perini G. Porro A, et al. Among authors: iraci n. Mol Cancer Res. 2011 Aug;9(8):1054-66. doi: 10.1158/1541-7786.MCR-10-0510. Epub 2011 Jun 21. Mol Cancer Res. 2011. PMID: 21693596
94 results