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Extracellular membrane vesicles and immune regulation in the brain.
Cossetti C, Smith JA, Iraci N, Leonardi T, Alfaro-Cervello C, Pluchino S. Cossetti C, et al. Among authors: iraci n. Front Physiol. 2012 May 1;3:117. doi: 10.3389/fphys.2012.00117. eCollection 2012. Front Physiol. 2012. PMID: 22557978 Free PMC article.
The stem cell secretome and its role in brain repair.
Drago D, Cossetti C, Iraci N, Gaude E, Musco G, Bachi A, Pluchino S. Drago D, et al. Among authors: iraci n. Biochimie. 2013 Dec;95(12):2271-85. doi: 10.1016/j.biochi.2013.06.020. Epub 2013 Jul 1. Biochimie. 2013. PMID: 23827856 Free PMC article. Review.
Extracellular vesicles from neural stem cells transfer IFN-γ via Ifngr1 to activate Stat1 signaling in target cells.
Cossetti C, Iraci N, Mercer TR, Leonardi T, Alpi E, Drago D, Alfaro-Cervello C, Saini HK, Davis MP, Schaeffer J, Vega B, Stefanini M, Zhao C, Muller W, Garcia-Verdugo JM, Mathivanan S, Bachi A, Enright AJ, Mattick JS, Pluchino S. Cossetti C, et al. Among authors: iraci n. Mol Cell. 2014 Oct 23;56(2):193-204. doi: 10.1016/j.molcel.2014.08.020. Epub 2014 Sep 18. Mol Cell. 2014. PMID: 25242146 Free PMC article.
Extracellular vesicles are independent metabolic units with asparaginase activity.
Iraci N, Gaude E, Leonardi T, Costa ASH, Cossetti C, Peruzzotti-Jametti L, Bernstock JD, Saini HK, Gelati M, Vescovi AL, Bastos C, Faria N, Occhipinti LG, Enright AJ, Frezza C, Pluchino S. Iraci N, et al. Nat Chem Biol. 2017 Sep;13(9):951-955. doi: 10.1038/nchembio.2422. Epub 2017 Jul 3. Nat Chem Biol. 2017. PMID: 28671681 Free PMC article.
A novel community driven software for functional enrichment analysis of extracellular vesicles data.
Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T, Liang Y, Llorente A, Lunavat TR, Maji S, Monteleone F, Øverbye A, Panaretakis T, Patel T, Peinado H, Pluchino S, Principe S, Ronquist G, Royo F, Sahoo S, Spinelli C, Stensballe A, Théry C, van Herwijnen MJC, Wauben M, Welton JL, Zhao K, Mathivanan S. Pathan M, et al. Among authors: iraci n. J Extracell Vesicles. 2017 May 26;6(1):1321455. doi: 10.1080/20013078.2017.1321455. eCollection 2017. J Extracell Vesicles. 2017. PMID: 28717418 Free PMC article.
Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation.
Peruzzotti-Jametti L, Bernstock JD, Vicario N, Costa ASH, Kwok CK, Leonardi T, Booty LM, Bicci I, Balzarotti B, Volpe G, Mallucci G, Manferrari G, Donegà M, Iraci N, Braga A, Hallenbeck JM, Murphy MP, Edenhofer F, Frezza C, Pluchino S. Peruzzotti-Jametti L, et al. Among authors: iraci n. Cell Stem Cell. 2018 Mar 1;22(3):355-368.e13. doi: 10.1016/j.stem.2018.01.020. Epub 2018 Feb 22. Cell Stem Cell. 2018. PMID: 29478844 Free PMC article.
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