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Blocking FSH induces thermogenic adipose tissue and reduces body fat.
Liu P, Ji Y, Yuen T, Rendina-Ruedy E, DeMambro VE, Dhawan S, Abu-Amer W, Izadmehr S, Zhou B, Shin AC, Latif R, Thangeswaran P, Gupta A, Li J, Shnayder V, Robinson ST, Yu YE, Zhang X, Yang F, Lu P, Zhou Y, Zhu LL, Oberlin DJ, Davies TF, Reagan MR, Brown A, Kumar TR, Epstein S, Iqbal J, Avadhani NG, New MI, Molina H, van Klinken JB, Guo EX, Buettner C, Haider S, Bian Z, Sun L, Rosen CJ, Zaidi M. Liu P, et al. Among authors: iqbal j. Nature. 2017 Jun 1;546(7656):107-112. doi: 10.1038/nature22342. Epub 2017 May 24. Nature. 2017. PMID: 28538730 Free PMC article.
Commentary-FSH and bone 2010: evolving evidence.
Iqbal J, Sun L, Zaidi M. Iqbal J, et al. Eur J Endocrinol. 2010 Jul;163(1):173-6. doi: 10.1530/EJE-10-0397. Epub 2010 May 6. Eur J Endocrinol. 2010. PMID: 20448000
Epitope-specific monoclonal antibodies to FSHβ increase bone mass.
Ji Y, Liu P, Yuen T, Haider S, He J, Romero R, Chen H, Bloch M, Kim SM, Lizneva D, Munshi L, Zhou C, Lu P, Iqbal J, Cheng Z, New MI, Hsueh AJ, Bian Z, Rosen CJ, Sun L, Zaidi M. Ji Y, et al. Among authors: iqbal j. Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2192-2197. doi: 10.1073/pnas.1718144115. Epub 2018 Feb 12. Proc Natl Acad Sci U S A. 2018. PMID: 29440419 Free PMC article.
FSH, Bone Mass, Body Fat, and Biological Aging.
Zaidi M, Lizneva D, Kim SM, Sun L, Iqbal J, New MI, Rosen CJ, Yuen T. Zaidi M, et al. Among authors: iqbal j. Endocrinology. 2018 Oct 1;159(10):3503-3514. doi: 10.1210/en.2018-00601. Endocrinology. 2018. PMID: 30085049 Free PMC article.
FSH-metabolic circuitry and menopause.
Taneja C, Gera S, Kim SM, Iqbal J, Yuen T, Zaidi M. Taneja C, et al. Among authors: iqbal j. J Mol Endocrinol. 2019 Oct;63(3):R73-R80. doi: 10.1530/JME-19-0152. J Mol Endocrinol. 2019. PMID: 31454787 Free PMC article. Review.
First-in-class humanized FSH blocking antibody targets bone and fat.
Gera S, Sant D, Haider S, Korkmaz F, Kuo TC, Mathew M, Perez-Pena H, Xie H, Chen H, Batista R, Ma K, Cheng Z, Hadelia E, Robinson C, Macdonald A, Miyashita S, Williams A, Jebian G, Miyashita H, Gumerova A, Ievleva K, Smith P, He J, Ryu V, DeMambro V, Quinn MA, Meseck M, Kim SM, Kumar TR, Iqbal J, New MI, Lizneva D, Rosen CJ, Hsueh AJ, Yuen T, Zaidi M. Gera S, et al. Among authors: iqbal j. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28971-28979. doi: 10.1073/pnas.2014588117. Epub 2020 Oct 30. Proc Natl Acad Sci U S A. 2020. PMID: 33127753 Free PMC article.
FSH blockade improves cognition in mice with Alzheimer's disease.
Xiong J, Kang SS, Wang Z, Liu X, Kuo TC, Korkmaz F, Padilla A, Miyashita S, Chan P, Zhang Z, Katsel P, Burgess J, Gumerova A, Ievleva K, Sant D, Yu SP, Muradova V, Frolinger T, Lizneva D, Iqbal J, Goosens KA, Gera S, Rosen CJ, Haroutunian V, Ryu V, Yuen T, Zaidi M, Ye K. Xiong J, et al. Among authors: iqbal j. Nature. 2022 Mar;603(7901):470-476. doi: 10.1038/s41586-022-04463-0. Epub 2022 Mar 2. Nature. 2022. PMID: 35236988 Free PMC article.
FSH directly regulates bone mass.
Sun L, Peng Y, Sharrow AC, Iqbal J, Zhang Z, Papachristou DJ, Zaidi S, Zhu LL, Yaroslavskiy BB, Zhou H, Zallone A, Sairam MR, Kumar TR, Bo W, Braun J, Cardoso-Landa L, Schaffler MB, Moonga BS, Blair HC, Zaidi M. Sun L, et al. Among authors: iqbal j. Cell. 2006 Apr 21;125(2):247-60. doi: 10.1016/j.cell.2006.01.051. Cell. 2006. PMID: 16630814 Free article.
Regulation of FSH receptor promoter activation in the osteoclast.
Zaidi S, Zhu LL, Mali R, Iqbal J, Yang G, Zaidi M, Sun L. Zaidi S, et al. Among authors: iqbal j. Biochem Biophys Res Commun. 2007 Oct 5;361(4):910-5. doi: 10.1016/j.bbrc.2007.07.081. Epub 2007 Jul 24. Biochem Biophys Res Commun. 2007. PMID: 17681281
1,912 results