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Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice.
Nat Commun. 2022 Nov 8;13(1):6742. doi: 10.1038/s41467-022-34582-1.
Nat Commun. 2022.
PMID: 36347873
Free PMC article.
Synthesis of novel methyl jasmonate derivatives and evaluation of their biological activity in various cancer cell lines.
Sucu BO, Ipek OS, Kurtulus SO, Yazici BE, Karakas N, Guzel M.
Sucu BO, et al. Among authors: ipek os.
Bioorg Chem. 2019 Oct;91:103146. doi: 10.1016/j.bioorg.2019.103146. Epub 2019 Jul 26.
Bioorg Chem. 2019.
PMID: 31377389
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Design and synthesis of novel cylopentapyrazoles bearing 1,2,3-thiadiazole moiety as potent antifungal agents.
Giray B, Karadağ AE, İpek ÖŞ, Pekel H, Güzel M, Küçük HB.
Giray B, et al. Among authors: ipek os.
Bioorg Chem. 2020 Jan;95:103509. doi: 10.1016/j.bioorg.2019.103509. Epub 2019 Dec 24.
Bioorg Chem. 2020.
PMID: 31884141
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TW68, cryptochromes stabilizer, regulates fasting blood glucose levels in diabetic ob/ob and high fat-diet-induced obese mice.
Surme S, Ergun C, Gul S, Akyel YK, Gul ZM, Ozcan O, Ipek OS, Akarlar BA, Ozlu N, Taskin AC, Turkay M, Gören AC, Baris I, Ozturk N, Guzel M, Aydin C, Okyar A, Kavakli IH.
Surme S, et al. Among authors: ipek os.
Biochem Pharmacol. 2023 Dec;218:115896. doi: 10.1016/j.bcp.2023.115896. Epub 2023 Oct 28.
Biochem Pharmacol. 2023.
PMID: 37898388
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