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A guideline on the molecular ecosystem regulating ferroptosis.
Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, Bayir H, Yang WS, Garcia-Saez AJ, Ioannou MS, Janowitz T, Ran Q, Gu W, Gan B, Krysko DV, Zhu X, Wang J, Krautwald S, Toyokuni S, Xie Y, Greten FR, Yi Q, Schick J, Liu J, Gabrilovich DI, Liu J, Zeh HJ, Zhang DD, Yang M, Iovanna J, Kopf M, Adolph TE, Chi JT, Li C, Ichijo H, Karin M, Sankaran VG, Zou W, Galluzzi L, Bush AI, Li B, Melino G, Baehrecke EH, Lotze MT, Klionsky DJ, Stockwell BR, Kroemer G, Tang D. Dai E, et al. Among authors: iovanna j. Nat Cell Biol. 2024 Feb 29. doi: 10.1038/s41556-024-01360-8. Online ahead of print. Nat Cell Biol. 2024. PMID: 38424270 Review.
Pacpaint: a histology-based deep learning model uncovers the extensive intratumor molecular heterogeneity of pancreatic adenocarcinoma.
Saillard C, Delecourt F, Schmauch B, Moindrot O, Svrcek M, Bardier-Dupas A, Emile JF, Ayadi M, Rebours V, de Mestier L, Hammel P, Neuzillet C, Bachet JB, Iovanna J, Dusetti N, Blum Y, Richard M, Kermezli Y, Paradis V, Zaslavskiy M, Courtiol P, Kamoun A, Nicolle R, Cros J. Saillard C, et al. Among authors: iovanna j. Nat Commun. 2023 Jun 13;14(1):3459. doi: 10.1038/s41467-023-39026-y. Nat Commun. 2023. PMID: 37311751 Free PMC article.
Activation of lysosomal iron triggers ferroptosis in cancer.
Rodriguez R, Cañeque T, Baron L, Müller S, Carmona A, Colombeau L, Versini A, Sabatier M, Sampaio J, Mishima E, Picard-Bernes A, Solier S, Zheng J, Proneth B, Thoidingjam L, Gaillet C, Grimaud L, Fraser C, Szylo K, Bonnet C, Charafe E, Ginestier C, Santofimia P, Dusetti N, Iovanna J, Sa Cunha A, Pittau G, Hammel P, Tzanis D, Bonvalot S, Watson S, Stockwell B, Conrad M, Ubellacker J. Rodriguez R, et al. Among authors: iovanna j. Res Sq [Preprint]. 2024 Apr 8:rs.3.rs-4165774. doi: 10.21203/rs.3.rs-4165774/v1. Res Sq. 2024. PMID: 38659936 Free PMC article. Preprint.
Combining the antianginal drug perhexiline with chemotherapy induces complete pancreatic cancer regression in vivo.
Reyes-Castellanos G, Abdel Hadi N, Gallardo-Arriaga S, Masoud R, Garcia J, Lac S, El Kaoutari A, Gicquel T, Planque M, Fendt SM, Linares LK, Gayet O, Guillaumond F, Dusetti N, Iovanna J, Carrier A. Reyes-Castellanos G, et al. Among authors: iovanna j. iScience. 2023 May 19;26(6):106899. doi: 10.1016/j.isci.2023.106899. eCollection 2023 Jun 16. iScience. 2023. PMID: 37305702 Free PMC article.
GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1.
Almada LL, Barroso K, Sen S, Toruner M, Sigafoos AN, Raja Arul GL, Pease DR, Vera RE, Olson RLO, Auner HW, Pedeux R, Iovanna JL, Chevet E, Fernandez-Zapico ME. Almada LL, et al. Biochim Biophys Acta Gene Regul Mech. 2023 Jun;1866(2):194924. doi: 10.1016/j.bbagrm.2023.194924. Epub 2023 Feb 25. Biochim Biophys Acta Gene Regul Mech. 2023. PMID: 36842643 Free article.
Intrinsically Disordered Chromatin Protein NUPR1 Binds to the Enzyme PADI4.
Araujo-Abad S, Neira JL, Rizzuti B, García-Morales P, de Juan Romero C, Santofimia-Castaño P, Iovanna J. Araujo-Abad S, et al. Among authors: iovanna j. J Mol Biol. 2023 Apr 15;435(8):168033. doi: 10.1016/j.jmb.2023.168033. Epub 2023 Feb 27. J Mol Biol. 2023. PMID: 36858171 Free article.
Cargo-selective and adaptive delivery of nucleic acid therapeutics by bola-amphiphilic dendrimers.
Chen J, Zhu D, Lian B, Shi K, Chen P, Li Y, Lin W, Ding L, Long Q, Wang Y, Laurini E, Lan W, Li Y, Tintaru A, Ju C, Zhang C, Pricl S, Iovanna J, Liu X, Peng L. Chen J, et al. Among authors: iovanna j. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2220787120. doi: 10.1073/pnas.2220787120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186846 Free PMC article.
462 results