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Page 1
Phenotypic plasticity and genetic control in colorectal cancer evolution.
Househam J, Heide T, Cresswell GD, Spiteri I, Kimberley C, Zapata L, Lynn C, James C, Mossner M, Fernandez-Mateos J, Vinceti A, Baker AM, Gabbutt C, Berner A, Schmidt M, Chen B, Lakatos E, Gunasri V, Nichol D, Costa H, Mitchinson M, Ramazzotti D, Werner B, Iorio F, Jansen M, Caravagna G, Barnes CP, Shibata D, Bridgewater J, Rodriguez-Justo M, Magnani L, Sottoriva A, Graham TA. Househam J, et al. Among authors: iorio f. Nature. 2022 Nov;611(7937):744-753. doi: 10.1038/s41586-022-05311-x. Epub 2022 Oct 26. Nature. 2022. PMID: 36289336 Free PMC article.
Transcriptional gene network inference from a massive dataset elucidates transcriptome organization and gene function.
Belcastro V, Siciliano V, Gregoretti F, Mithbaokar P, Dharmalingam G, Berlingieri S, Iorio F, Oliva G, Polishchuck R, Brunetti-Pierri N, di Bernardo D. Belcastro V, et al. Among authors: iorio f. Nucleic Acids Res. 2011 Nov 1;39(20):8677-88. doi: 10.1093/nar/gkr593. Epub 2011 Jul 23. Nucleic Acids Res. 2011. PMID: 21785136 Free PMC article.
Unravelling druggable signalling networks that control F508del-CFTR proteostasis.
Hegde RN, Parashuraman S, Iorio F, Ciciriello F, Capuani F, Carissimo A, Carrella D, Belcastro V, Subramanian A, Bounti L, Persico M, Carlile G, Galietta L, Thomas DY, Di Bernardo D, Luini A. Hegde RN, et al. Among authors: iorio f. Elife. 2015 Dec 23;4:e10365. doi: 10.7554/eLife.10365. Elife. 2015. PMID: 26701908 Free PMC article.
Fast randomization of large genomic datasets while preserving alteration counts.
Gobbi A, Iorio F, Dawson KJ, Wedge DC, Tamborero D, Alexandrov LB, Lopez-Bigas N, Garnett MJ, Jurman G, Saez-Rodriguez J. Gobbi A, et al. Among authors: iorio f. Bioinformatics. 2014 Sep 1;30(17):i617-23. doi: 10.1093/bioinformatics/btu474. Bioinformatics. 2014. PMID: 25161255 Free PMC article.
Interactive data analysis and clustering of genomic data.
Ciaramella A, Cocozza S, Iorio F, Miele G, Napolitano F, Pinelli M, Raiconi G, Tagliaferri R. Ciaramella A, et al. Among authors: iorio f. Neural Netw. 2008 Mar-Apr;21(2-3):368-78. doi: 10.1016/j.neunet.2007.12.026. Epub 2007 Dec 31. Neural Netw. 2008. PMID: 18255261
The germline genetic component of drug sensitivity in cancer cell lines.
Menden MP, Casale FP, Stephan J, Bignell GR, Iorio F, McDermott U, Garnett MJ, Saez-Rodriguez J, Stegle O. Menden MP, et al. Among authors: iorio f. Nat Commun. 2018 Aug 23;9(1):3385. doi: 10.1038/s41467-018-05811-3. Nat Commun. 2018. PMID: 30139972 Free PMC article.
Integrated cross-study datasets of genetic dependencies in cancer.
Pacini C, Dempster JM, Boyle I, Gonçalves E, Najgebauer H, Karakoc E, van der Meer D, Barthorpe A, Lightfoot H, Jaaks P, McFarland JM, Garnett MJ, Tsherniak A, Iorio F. Pacini C, et al. Among authors: iorio f. Nat Commun. 2021 Mar 12;12(1):1661. doi: 10.1038/s41467-021-21898-7. Nat Commun. 2021. PMID: 33712601 Free PMC article.
180 results