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Hepatic insulin clearance is the primary determinant of insulin sensitivity in the normal dog.
Ader M, Stefanovski D, Kim SP, Richey JM, Ionut V, Catalano KJ, Hucking K, Ellmerer M, Van Citters G, Hsu IR, Chiu JD, Woolcott OO, Harrison LN, Zheng D, Lottati M, Kolka CM, Mooradian V, Dittmann J, Yae S, Liu H, Castro AV, Kabir M, Bergman RN. Ader M, et al. Among authors: ionut v. Obesity (Silver Spring). 2014 May;22(5):1238-45. doi: 10.1002/oby.20625. Epub 2013 Dec 3. Obesity (Silver Spring). 2014. PMID: 24123967 Free PMC article.
Large size cells in the visceral adipose depot predict insulin resistance in the canine model.
Kabir M, Stefanovski D, Hsu IR, Iyer M, Woolcott OO, Zheng D, Catalano KJ, Chiu JD, Kim SP, Harrison LN, Ionut V, Lottati M, Bergman RN, Richey JM. Kabir M, et al. Among authors: ionut v. Obesity (Silver Spring). 2011 Nov;19(11):2121-9. doi: 10.1038/oby.2011.254. Epub 2011 Aug 11. Obesity (Silver Spring). 2011. PMID: 21836643 Free PMC article.
Increase in visceral fat per se does not induce insulin resistance in the canine model.
Castro AV, Woolcott OO, Iyer MS, Kabir M, Ionut V, Stefanovski D, Kolka CM, Szczepaniak LS, Szczepaniak EW, Asare-Bediako I, Paszkiewicz RL, Broussard JL, Kim SP, Kirkman EL, Rios HC, Mkrtchyan H, Wu Q, Ader M, Bergman RN. Castro AV, et al. Among authors: ionut v. Obesity (Silver Spring). 2015 Jan;23(1):105-11. doi: 10.1002/oby.20906. Epub 2014 Oct 16. Obesity (Silver Spring). 2015. PMID: 25322680 Free PMC article.
Novel canine models of obese prediabetes and mild type 2 diabetes.
Ionut V, Liu H, Mooradian V, Castro AV, Kabir M, Stefanovski D, Zheng D, Kirkman EL, Bergman RN. Ionut V, et al. Am J Physiol Endocrinol Metab. 2010 Jan;298(1):E38-48. doi: 10.1152/ajpendo.00466.2009. Epub 2009 Oct 20. Am J Physiol Endocrinol Metab. 2010. PMID: 19843874 Free PMC article.
27 results