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Surface patches induce nonspecific binding and phase separation of antibodies.
Ausserwöger H, Krainer G, Welsh TJ, Thorsteinson N, de Csilléry E, Sneideris T, Schneider MM, Egebjerg T, Invernizzi G, Herling TW, Lorenzen N, Knowles TPJ. Ausserwöger H, et al. Among authors: invernizzi g. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2210332120. doi: 10.1073/pnas.2210332120. Epub 2023 Apr 3. Proc Natl Acad Sci U S A. 2023. PMID: 37011217 Free PMC article.
Non-specificity as the sticky problem in therapeutic antibody development.
Ausserwöger H, Schneider MM, Herling TW, Arosio P, Invernizzi G, Knowles TPJ, Lorenzen N. Ausserwöger H, et al. Among authors: invernizzi g. Nat Rev Chem. 2022 Dec;6(12):844-861. doi: 10.1038/s41570-022-00438-x. Epub 2022 Nov 14. Nat Rev Chem. 2022. PMID: 37117703 Review.
Nonspecificity fingerprints for clinical-stage antibodies in solution.
Herling TW, Invernizzi G, Ausserwöger H, Bjelke JR, Egebjerg T, Lund S, Lorenzen N, Knowles TPJ. Herling TW, et al. Among authors: invernizzi g. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2306700120. doi: 10.1073/pnas.2306700120. Epub 2023 Dec 18. Proc Natl Acad Sci U S A. 2023. PMID: 38109540
An integrated platform approach enables discovery of potent, selective and ligand-competitive cyclic peptides targeting the GIP receptor.
Bhushan B, Granata D, Kaas CS, Kasimova MA, Ren Q, Cramer CN, White MD, Hansen AMK, Fledelius C, Invernizzi G, Deibler K, Coleman OD, Zhao X, Qu X, Liu H, Zurmühl SS, Kodra JT, Kawamura A, Münzel M. Bhushan B, et al. Among authors: invernizzi g. Chem Sci. 2022 Feb 24;13(11):3256-3262. doi: 10.1039/d1sc06844j. eCollection 2022 Mar 16. Chem Sci. 2022. PMID: 35414877 Free PMC article.
Ubiquitin Interacting Motifs: Duality Between Structured and Disordered Motifs.
Lambrughi M, Maiani E, Aykac Fas B, Shaw GS, Kragelund BB, Lindorff-Larsen K, Teilum K, Invernizzi G, Papaleo E. Lambrughi M, et al. Among authors: invernizzi g. Front Mol Biosci. 2021 Jun 28;8:676235. doi: 10.3389/fmolb.2021.676235. eCollection 2021. Front Mol Biosci. 2021. PMID: 34262938 Free PMC article.
The effects of superoxide dismutase-rich melon pulp concentrate on inflammation, antioxidant status and growth performance of challenged post-weaning piglets.
Ahasan ASML, Invernizzi G, Farina G, Pilotto A, Barbé F, Bontempo V, Rossi R, Bellagamba F, Lecchi C, Savoini G, Agazzi A. Ahasan ASML, et al. Among authors: invernizzi g. Animal. 2019 Jan;13(1):136-143. doi: 10.1017/S1751731118001234. Epub 2018 Jun 18. Animal. 2019. PMID: 29909802 Free article.
261 results