Type VII secretion system extracellular protein B targets STING to evade host anti-Staphylococcus aureus immunity.
Gao L, Tian T, Xiong T, Zhang X, Wang N, Liu L, Shi Y, Liu Q, Lu D, Luo P, Zhang W, Cheng P, Gou Q, Wang Y, Zeng H, Zhang X, Zou Q.
Gao L, et al.
Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2402764121. doi: 10.1073/pnas.2402764121. Epub 2024 May 21.
Proc Natl Acad Sci U S A. 2024.
PMID: 38771879
Here, we demonstrate that in infected host cells, S. aureus type VII secretion system (T7SS) extracellular protein B (EsxB) interacts with the stimulator of interferon genes (STING) protein and suppresses the inflammatory defense mechanism of macrophages during early infec …
Here, we demonstrate that in infected host cells, S. aureus type VII secretion system (T7SS) extracellular protein B (EsxB) interacts …