Inoue A - Search Results

1

Identification and pharmacological characterization of succinate receptor agonists.

Geubelle P, Gilissen J, Dilly S, Poma L, Dupuis N, Laschet C, Abboud D, Inoue A, Jouret F, Pirotte B, Hanson J. Geubelle P, et al. Among authors: inoue a. Br J Pharmacol. 2017 May;174(9):796-808. doi: 10.1111/bph.13738. Epub 2017 Mar 10. Br J Pharmacol. 2017. PMID: 28160606 Free PMC article.

2

Purinergic Receptor Transactivation by the β₂-Adrenergic Receptor Increases Intracellular Ca²⁺ in Nonexcitable Cells.

Stallaert W, van der Westhuizen ET, Schönegge AM, Plouffe B, Hogue M, Lukashova V, Inoue A, Ishida S, Aoki J, Le Gouill C, Bouvier M. Stallaert W, et al. Among authors: inoue a. Mol Pharmacol. 2017 May;91(5):533-544. doi: 10.1124/mol.116.106419. Epub 2017 Mar 9. Mol Pharmacol. 2017. PMID: 28280061

3

C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways.

Smith JS, Alagesan P, Desai NK, Pack TF, Wu JH, Inoue A, Freedman NJ, Rajagopal S. Smith JS, et al. Among authors: inoue a. Mol Pharmacol. 2017 Aug;92(2):136-150. doi: 10.1124/mol.117.108522. Epub 2017 May 30. Mol Pharmacol. 2017. PMID: 28559424 Free PMC article.

4

On the G protein-coupling selectivity of the native A_2B adenosine receptor.

Gao ZG, Inoue A, Jacobson KA. Gao ZG, et al. Among authors: inoue a. Biochem Pharmacol. 2018 May;151:201-213. doi: 10.1016/j.bcp.2017.12.003. Epub 2017 Dec 7. Biochem Pharmacol. 2018. PMID: 29225130 Free PMC article.

5

Cell-permeable high-affinity tracers for G_q proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

Kuschak M, Namasivayam V, Rafehi M, Voss JH, Garg J, Schlegel JG, Abdelrahman A, Kehraus S, Reher R, Küppers J, Sylvester K, Hinz S, Matthey M, Wenzel D, Fleischmann BK, Pfeifer A, Inoue A, Gütschow M, König GM, Müller CE. Kuschak M, et al. Among authors: inoue a. Br J Pharmacol. 2020 Apr;177(8):1898-1916. doi: 10.1111/bph.14960. Epub 2020 Feb 11. Br J Pharmacol. 2020. PMID: 31881095 Free PMC article.

6

GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of G_s and G_q/11.

Abboud D, Daly AF, Dupuis N, Bahri MA, Inoue A, Chevigné A, Ectors F, Plenevaux A, Pirotte B, Beckers A, Hanson J. Abboud D, et al. Among authors: inoue a. Nat Commun. 2020 Sep 21;11(1):4752. doi: 10.1038/s41467-020-18500-x. Nat Commun. 2020. PMID: 32958754 Free PMC article.

7

Switching Lysophosphatidylserine G Protein-Coupled Receptor Agonists to Antagonists by Acylation of the Hydrophilic Serine Amine.

Sayama M, Uwamizu A, Ikubo M, Chen L, Yan G, Otani Y, Inoue A, Aoki J, Ohwada T. Sayama M, et al. Among authors: inoue a. J Med Chem. 2021 Jul 22;64(14):10059-10101. doi: 10.1021/acs.jmedchem.1c00347. Epub 2021 Jul 7. J Med Chem. 2021. PMID: 34233115

8

Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor.

De Pascali F, Ayoub MA, Benevelli R, Sposini S, Lehoux J, Gallay N, Raynaud P, Landomiel F, Jean-Alphonse F, Gauthier C, Pellissier LP, Crépieux P, Poupon A, Inoue A, Joubert N, Viaud-Massuard MC, Casarini L, Simoni M, Hanyaloglu AC, Nataraja SG, Yu HN, Palmer SS, Yvinec R, Reiter E. De Pascali F, et al. Among authors: inoue a. Int J Mol Sci. 2021 Sep 12;22(18):9850. doi: 10.3390/ijms22189850. Int J Mol Sci. 2021. PMID: 34576014 Free PMC article.

9

Phenylalanine 193 in Extracellular Loop 2 of the β ₂-Adrenergic Receptor Coordinates β-Arrestin Interaction.

Ippolito M, De Pascali F, Inoue A, Benovic JL. Ippolito M, et al. Among authors: inoue a. Mol Pharmacol. 2022 Feb;101(2):87-94. doi: 10.1124/molpharm.121.000332. Epub 2021 Dec 1. Mol Pharmacol. 2022. PMID: 34853152 Free PMC article.

10

Phosphorothioate analogs of sn-2 radyl lysophosphatidic acid (LPA): metabolically stabilized LPA receptor agonists.

Jiang G, Inoue A, Aoki J, Prestwich GD. Jiang G, et al. Among authors: inoue a. Bioorg Med Chem Lett. 2013 Mar 15;23(6):1865-9. doi: 10.1016/j.bmcl.2013.01.002. Epub 2013 Jan 23. Bioorg Med Chem Lett. 2013. PMID: 23395664

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