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Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging.
Silva-Cayetano A, Fra-Bido S, Robert PA, Innocentin S, Burton AR, Watson EM, Lee JL, Webb LMC, Foster WS, McKenzie RCJ, Bignon A, Vanderleyden I, Alterauge D, Lemos JP, Carr EJ, Hill DL, Cinti I, Balabanian K, Baumjohann D, Espeli M, Meyer-Hermann M, Denton AE, Linterman MA. Silva-Cayetano A, et al. Among authors: innocentin s. Nat Immunol. 2023 Jul;24(7):1124-1137. doi: 10.1038/s41590-023-01519-9. Epub 2023 May 22. Nat Immunol. 2023. PMID: 37217705 Free PMC article.
GIMAP6 is required for T cell maintenance and efficient autophagy in mice.
Pascall JC, Webb LMC, Eskelinen EL, Innocentin S, Attaf-Bouabdallah N, Butcher GW. Pascall JC, et al. Among authors: innocentin s. PLoS One. 2018 May 2;13(5):e0196504. doi: 10.1371/journal.pone.0196504. eCollection 2018. PLoS One. 2018. PMID: 29718959 Free PMC article.
Type I interferon induces CXCL13 to support ectopic germinal center formation.
Denton AE, Innocentin S, Carr EJ, Bradford BM, Lafouresse F, Mabbott NA, Mörbe U, Ludewig B, Groom JR, Good-Jacobson KL, Linterman MA. Denton AE, et al. Among authors: innocentin s. J Exp Med. 2019 Mar 4;216(3):621-637. doi: 10.1084/jem.20181216. Epub 2019 Feb 5. J Exp Med. 2019. PMID: 30723095 Free PMC article.
Immune system development varies according to age, location, and anemia in African children.
Hill DL, Carr EJ, Rutishauser T, Moncunill G, Campo JJ, Innocentin S, Mpina M, Nhabomba A, Tumbo A, Jairoce C, Moll HA, van Zelm MC, Dobaño C, Daubenberger C, Linterman MA. Hill DL, et al. Among authors: innocentin s. Sci Transl Med. 2020 Feb 5;12(529):eaaw9522. doi: 10.1126/scitranslmed.aaw9522. Sci Transl Med. 2020. PMID: 32024802 Free PMC article.
A booster dose enhances immunogenicity of the COVID-19 vaccine candidate ChAdOx1 nCoV-19 in aged mice.
Silva-Cayetano A, Foster WS, Innocentin S, Belij-Rammerstorfer S, Spencer AJ, Burton OT, Fra-Bidó S, Le Lee J, Thakur N, Conceicao C, Wright D, Barrett J, Evans-Bailey N, Noble C, Bailey D, Liston A, Gilbert SC, Lambe T, Linterman MA. Silva-Cayetano A, et al. Among authors: innocentin s. Med. 2021 Mar 12;2(3):243-262.e8. doi: 10.1016/j.medj.2020.12.006. Epub 2020 Dec 16. Med. 2021. PMID: 33521747 Free PMC article.
26 results