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Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.
Garcia-Bermudez J, Baudrier L, Bayraktar EC, Shen Y, La K, Guarecuco R, Yucel B, Fiore D, Tavora B, Freinkman E, Chan SH, Lewis C, Min W, Inghirami G, Sabatini DM, Birsoy K. Garcia-Bermudez J, et al. Among authors: inghirami g. Nature. 2019 Mar;567(7746):118-122. doi: 10.1038/s41586-019-0945-5. Epub 2019 Feb 13. Nature. 2019. PMID: 30760928 Free PMC article.
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Laimer D, Dolznig H, Kollmann K, Vesely PW, Schlederer M, Merkel O, Schiefer AI, Hassler MR, Heider S, Amenitsch L, Thallinger C, Staber PB, Simonitsch-Klupp I, Artaker M, Lagger S, Turner SD, Pileri S, Piccaluga PP, Valent P, Messana K, Landra I, Weichhart T, Knapp S, Shehata M, Todaro M, Sexl V, Höfler G, Piva R, Medico E, Ruggeri BA, Cheng M, Eferl R, Egger G, Penninger JM, Jaeger U, Moriggl R, Inghirami G, Kenner L. Laimer D, et al. Among authors: inghirami g. Nat Med. 2012 Nov;18(11):1699-704. doi: 10.1038/nm.2966. Epub 2012 Oct 14. Nat Med. 2012. PMID: 23064464 Free article.
Epigenomic evolution in diffuse large B-cell lymphomas.
Pan H, Jiang Y, Boi M, Tabbò F, Redmond D, Nie K, Ladetto M, Chiappella A, Cerchietti L, Shaknovich R, Melnick AM, Inghirami GG, Tam W, Elemento O. Pan H, et al. Among authors: inghirami gg. Nat Commun. 2015 Apr 20;6:6921. doi: 10.1038/ncomms7921. Nat Commun. 2015. PMID: 25891015 Free PMC article.
The heterogeneous landscape of ALK negative ALCL.
Mereu E, Pellegrino E, Scarfò I, Inghirami G, Piva R. Mereu E, et al. Among authors: inghirami g. Oncotarget. 2017 Mar 14;8(11):18525-18536. doi: 10.18632/oncotarget.14503. Oncotarget. 2017. PMID: 28061468 Free PMC article. Review.
Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas.
Abate F, da Silva-Almeida AC, Zairis S, Robles-Valero J, Couronne L, Khiabanian H, Quinn SA, Kim MY, Laginestra MA, Kim C, Fiore D, Bhagat G, Piris MA, Campo E, Lossos IS, Bernard OA, Inghirami G, Pileri S, Bustelo XR, Rabadan R, Ferrando AA, Palomero T. Abate F, et al. Among authors: inghirami g. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):764-769. doi: 10.1073/pnas.1608839114. Epub 2017 Jan 6. Proc Natl Acad Sci U S A. 2017. PMID: 28062691 Free PMC article.
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors.
Cayrol F, Praditsuktavorn P, Fernando TM, Kwiatkowski N, Marullo R, Calvo-Vidal MN, Phillip J, Pera B, Yang SN, Takpradit K, Roman L, Gaudiano M, Crescenzo R, Ruan J, Inghirami G, Zhang T, Cremaschi G, Gray NS, Cerchietti L. Cayrol F, et al. Among authors: inghirami g. Nat Commun. 2017 Jan 30;8:14290. doi: 10.1038/ncomms14290. Nat Commun. 2017. PMID: 28134252 Free PMC article.
321 results