Ingelman-Sundberg M - Search Results

1

Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates.

Lauschke VM, Hendriks DF, Bell CC, Andersson TB, Ingelman-Sundberg M. Lauschke VM, et al. Chem Res Toxicol. 2016 Dec 19;29(12):1936-1955. doi: 10.1021/acs.chemrestox.6b00150. Epub 2016 Sep 23. Chem Res Toxicol. 2016. PMID: 27661221 Review.

2

Interindividual differences in hepatic expression of CYP3A4: relationship to genetic polymorphism in the 5'-upstream regulatory region.

Westlind A, Löfberg L, Tindberg N, Andersson TB, Ingelman-Sundberg M. Westlind A, et al. Biochem Biophys Res Commun. 1999 May 27;259(1):201-5. doi: 10.1006/bbrc.1999.0752. Biochem Biophys Res Commun. 1999. PMID: 10334940

3

Cloning and tissue distribution of a novel human cytochrome p450 of the CYP3A subfamily, CYP3A43.

Westlind A, Malmebo S, Johansson I, Otter C, Andersson TB, Ingelman-Sundberg M, Oscarson M. Westlind A, et al. Biochem Biophys Res Commun. 2001 Mar;281(5):1349-55. doi: 10.1006/bbrc.2001.4505. Biochem Biophys Res Commun. 2001. PMID: 11243885

4

An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant.

Andersson TB, Sjöberg H, Hoffmann KJ, Boobis AR, Watts P, Edwards RJ, Lake BG, Price RJ, Renwick AB, Gómez-Lechón MJ, Castell JV, Ingelman-Sundberg M, Hidestrand M, Goldfarb PS, Lewis DF, Corcos L, Guillouzo A, Taavitsainen P, Pelkonen O. Andersson TB, et al. Drug Metab Dispos. 2001 May;29(5):712-20. Drug Metab Dispos. 2001. PMID: 11302938

5

Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism.

Westlind-Johnsson A, Malmebo S, Johansson A, Otter C, Andersson TB, Johansson I, Edwards RJ, Boobis AR, Ingelman-Sundberg M. Westlind-Johnsson A, et al. Drug Metab Dispos. 2003 Jun;31(6):755-61. doi: 10.1124/dmd.31.6.755. Drug Metab Dispos. 2003. PMID: 12756208

6

Characterization and partial purification of the rat and human enzyme systems active in the reduction of N-hydroxymelagatran and benzamidoxime.

Andersson S, Hofmann Y, Nordling A, Li XQ, Nivelius S, Andersson TB, Ingelman-Sundberg M, Johansson I. Andersson S, et al. Drug Metab Dispos. 2005 Apr;33(4):570-8. doi: 10.1124/dmd.104.002972. Epub 2005 Jan 7. Drug Metab Dispos. 2005. PMID: 15640373

7

Expression of drug metabolizing enzymes in hepatocyte-like cells derived from human embryonic stem cells.

Ek M, Söderdahl T, Küppers-Munther B, Edsbagge J, Andersson TB, Björquist P, Cotgreave I, Jernström B, Ingelman-Sundberg M, Johansson I. Ek M, et al. Biochem Pharmacol. 2007 Aug 1;74(3):496-503. doi: 10.1016/j.bcp.2007.05.009. Epub 2007 May 17. Biochem Pharmacol. 2007. PMID: 17568565

8

Pro-inflammatory response and adverse drug reactions: mechanisms of action of ximelagatran on chemokine and cytokine activation in a monocyte in vitro model.

Edling Y, Sivertsson L, Andersson TB, Porsmyr-Palmertz M, Ingelman-Sundberg M. Edling Y, et al. Toxicol In Vitro. 2008 Sep;22(6):1588-94. doi: 10.1016/j.tiv.2008.06.011. Epub 2008 Jul 2. Toxicol In Vitro. 2008. PMID: 18640260

9

Increased sensitivity for troglitazone-induced cytotoxicity using a human in vitro co-culture model.

Edling Y, Sivertsson LK, Butura A, Ingelman-Sundberg M, Ek M. Edling Y, et al. Toxicol In Vitro. 2009 Oct;23(7):1387-95. doi: 10.1016/j.tiv.2009.07.026. Epub 2009 Jul 23. Toxicol In Vitro. 2009. PMID: 19631733

10

Hepatocyte-like cells derived from human embryonic stem cells specifically via definitive endoderm and a progenitor stage.

Brolén G, Sivertsson L, Björquist P, Eriksson G, Ek M, Semb H, Johansson I, Andersson TB, Ingelman-Sundberg M, Heins N. Brolén G, et al. J Biotechnol. 2010 Feb 1;145(3):284-94. doi: 10.1016/j.jbiotec.2009.11.007. Epub 2009 Nov 20. J Biotechnol. 2010. PMID: 19932139

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