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Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer's disease and neurodegeneration stratified by sex.
Cumplido-Mayoral I, García-Prat M, Operto G, Falcon C, Shekari M, Cacciaglia R, Milà-Alomà M, Lorenzini L, Ingala S, Meije Wink A, Mutsaerts HJMM, Minguillón C, Fauria K, Molinuevo JL, Haller S, Chetelat G, Waldman A, Schwarz AJ, Barkhof F, Suridjan I, Kollmorgen G, Bayfield A, Zetterberg H, Blennow K, Suárez-Calvet M, Vilaplana V, Gispert JD; ALFA study; EPAD study; ADNI study; OASIS study. Cumplido-Mayoral I, et al. Among authors: ingala s. Elife. 2023 Apr 17;12:e81067. doi: 10.7554/eLife.81067. Elife. 2023. PMID: 37067031 Free PMC article.
Secondary prevention of Alzheimer's dementia: neuroimaging contributions.
Ten Kate M, Ingala S, Schwarz AJ, Fox NC, Chételat G, van Berckel BNM, Ewers M, Foley C, Gispert JD, Hill D, Irizarry MC, Lammertsma AA, Molinuevo JL, Ritchie C, Scheltens P, Schmidt ME, Visser PJ, Waldman A, Wardlaw J, Haller S, Barkhof F. Ten Kate M, et al. Among authors: ingala s. Alzheimers Res Ther. 2018 Oct 30;10(1):112. doi: 10.1186/s13195-018-0438-z. Alzheimers Res Ther. 2018. PMID: 30376881 Free PMC article. Review.
Multi-study validation of data-driven disease progression models to characterize evolution of biomarkers in Alzheimer's disease.
Archetti D, Ingala S, Venkatraghavan V, Wottschel V, Young AL, Bellio M, Bron EE, Klein S, Barkhof F, Alexander DC, Oxtoby NP, Frisoni GB, Redolfi A; Alzheimer's Disease Neuroimaging Initiative; for EuroPOND Consortium. Archetti D, et al. Among authors: ingala s. Neuroimage Clin. 2019;24:101954. doi: 10.1016/j.nicl.2019.101954. Epub 2019 Jul 23. Neuroimage Clin. 2019. PMID: 31362149 Free PMC article.
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort: impact of AD risk factors and recruitment settings.
Vermunt L, Muniz-Terrera G, Ter Meulen L, Veal C, Blennow K, Campbell A, Carrié I, Delrieu J, Fauria K, Huesa Rodríguez G, Ingala S, Jenkins N, Molinuevo JL, Ousset PJ, Porteous D, Prins ND, Solomon A, Tom BD, Zetterberg H, Zwan M, Ritchie CW, Scheltens P, Luscan G, Brookes AJ, Visser PJ; IMI-EPAD collaborators. Vermunt L, et al. Among authors: ingala s. Alzheimers Res Ther. 2020 Jan 6;12(1):8. doi: 10.1186/s13195-019-0576-y. Alzheimers Res Ther. 2020. PMID: 31907067 Free PMC article.
Multitracer model for staging cortical amyloid deposition using PET imaging.
Collij LE, Heeman F, Salvadó G, Ingala S, Altomare D, de Wilde A, Konijnenberg E, van Buchem M, Yaqub M, Markiewicz P, Golla SSV, Wottschel V, Wink AM, Visser PJ, Teunissen CE, Lammertsma AA, Scheltens P, van der Flier WM, Boellaard R, van Berckel BNM, Molinuevo JL, Gispert JD, Schmidt ME, Barkhof F, Lopes Alves I; ALFA Study, for the Alzheimer's Disease Neuroimaging Initiative; AMYPAD Consortium. Collij LE, et al. Among authors: ingala s. Neurology. 2020 Sep 15;95(11):e1538-e1553. doi: 10.1212/WNL.0000000000010256. Epub 2020 Jul 16. Neurology. 2020. PMID: 32675080 Free PMC article.
DHA intake relates to better cerebrovascular and neurodegeneration neuroimaging phenotypes in middle-aged adults at increased genetic risk of Alzheimer disease.
Sala-Vila A, Arenaza-Urquijo EM, Sánchez-Benavides G, Suárez-Calvet M, Milà-Alomà M, Grau-Rivera O, González-de-Echávarri JM, Crous-Bou M, Minguillón C, Fauria K, Operto G, Falcón C, Salvadó G, Cacciaglia R, Ingala S, Barkhof F, Schröder H, Scarmeas N, Gispert JD, Molinuevo JL; ALFA study. Sala-Vila A, et al. Among authors: ingala s. Am J Clin Nutr. 2021 Jun 1;113(6):1627-1635. doi: 10.1093/ajcn/nqab016. Am J Clin Nutr. 2021. PMID: 33733657 Free PMC article.
Application of the ATN classification scheme in a population without dementia: Findings from the EPAD cohort.
Ingala S, De Boer C, Masselink LA, Vergari I, Lorenzini L, Blennow K, Chételat G, Di Perri C, Ewers M, van der Flier WM, Fox NC, Gispert JD, Haller S, Molinuevo JL, Muniz-Terrera G, Mutsaerts HJ, Ritchie CW, Ritchie K, Schmidt M, Schwarz AJ, Vermunt L, Waldman AD, Wardlaw J, Wink AM, Wolz R, Wottschel V, Scheltens P, Visser PJ, Barkhof F; EPAD consortium. Ingala S, et al. Alzheimers Dement. 2021 Jul;17(7):1189-1204. doi: 10.1002/alz.12292. Epub 2021 Apr 3. Alzheimers Dement. 2021. PMID: 33811742 Free PMC article.
Regional associations of white matter hyperintensities and early cortical amyloid pathology.
Lorenzini L, Ansems LT, Lopes Alves I, Ingala S, Vállez García D, Tomassen J, Sudre C, Salvadó G, Shekari M, Operto G, Brugulat-Serrat A, Sánchez-Benavides G, Ten Kate M, Tijms B, Wink AM, Mutsaerts HJMM, den Braber A, Visser PJ, van Berckel BNM, Gispert JD, Barkhof F, Collij LE; EPAD consortium for the ALFA cohort. Lorenzini L, et al. Among authors: ingala s. Brain Commun. 2022 Jun 15;4(3):fcac150. doi: 10.1093/braincomms/fcac150. eCollection 2022. Brain Commun. 2022. PMID: 35783557 Free PMC article.
The Open-Access European Prevention of Alzheimer's Dementia (EPAD) MRI dataset and processing workflow.
Lorenzini L, Ingala S, Wink AM, Kuijer JPA, Wottschel V, Dijsselhof M, Sudre CH, Haller S, Molinuevo JL, Gispert JD, Cash DM, Thomas DL, Vos SB, Prados F, Petr J, Wolz R, Palombit A, Schwarz AJ, Chételat G, Payoux P, Di Perri C, Wardlaw JM, Frisoni GB, Foley C, Fox NC, Ritchie C, Pernet C, Waldman A, Barkhof F, Mutsaerts HJMM; EPAD consortium. Lorenzini L, et al. Among authors: ingala s. Neuroimage Clin. 2022;35:103106. doi: 10.1016/j.nicl.2022.103106. Epub 2022 Jul 7. Neuroimage Clin. 2022. PMID: 35839659 Free PMC article.
41 results