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Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma.
Lucarini V, Melaiu O, D'Amico S, Pastorino F, Tempora P, Scarsella M, Pezzullo M, De Ninno A, D'Oria V, Cilli M, Emionite L, Infante P, Di Marcotullio L, De Ioris MA, Barillari G, Alaggio R, Businaro L, Ponzoni M, Locatelli F, Fruci D. Lucarini V, et al. Among authors: infante p. J Exp Clin Cancer Res. 2022 Nov 17;41(1):326. doi: 10.1186/s13046-022-02525-9. J Exp Clin Cancer Res. 2022. PMID: 36397148 Free PMC article.
Yin-Yang strands of PCAF/Hedgehog axis in cancer control.
Infante P, Canettieri G, Gulino A, Di Marcotullio L. Infante P, et al. Trends Mol Med. 2014 Aug;20(8):416-8. doi: 10.1016/j.molmed.2014.05.003. Epub 2014 Jun 4. Trends Mol Med. 2014. PMID: 24906555
Targeting GLI factors to inhibit the Hedgehog pathway.
Infante P, Alfonsi R, Botta B, Mori M, Di Marcotullio L. Infante P, et al. Trends Pharmacol Sci. 2015 Aug;36(8):547-58. doi: 10.1016/j.tips.2015.05.006. Epub 2015 Jun 10. Trends Pharmacol Sci. 2015. PMID: 26072120 Review.
Insights into Gli Factors Ubiquitylation Methods.
Infante P, Alfonsi R, Di Marcotullio L. Infante P, et al. Methods Mol Biol. 2015;1322:131-46. doi: 10.1007/978-1-4939-2772-2_12. Methods Mol Biol. 2015. PMID: 26179045
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.
Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras CE, Carai A, Cucchi D, Abballe L, Besharat ZM, Catanzaro G, Infante P, Di Marcotullio L, Canettieri G, De Smaele E, Screpanti I, Locatelli F, Ferretti E. Miele E, et al. Among authors: infante p. BMC Cancer. 2017 Jul 17;17(1):488. doi: 10.1186/s12885-017-3477-0. BMC Cancer. 2017. PMID: 28716052 Free PMC article.
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors.
Petroni M, Sardina F, Infante P, Bartolazzi A, Locatelli E, Fabretti F, Di Giulio S, Capalbo C, Cardinali B, Coppa A, Tessitore A, Colicchia V, Sahùn Roncero M, Belardinilli F, Di Marcotullio L, Soddu S, Comes Franchini M, Petricci E, Gulino A, Giannini G. Petroni M, et al. Among authors: infante p. Cell Death Dis. 2018 Aug 30;9(9):895. doi: 10.1038/s41419-018-0924-z. Cell Death Dis. 2018. PMID: 30166519 Free PMC article.
162 results