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Determination of five positive control drugs in hERG external solution (buffer) by LC-MS/MS to support in vitro hERG assay as recommended by ICH S7B.
King TI, Indapurkar A, Tariq I, DePalma R, Mistry S, Alvarez-Baron C, Ismaiel OA, Wu W, Chiu K, Patel V, Rouse R, Strauss DG, Matta MK. King TI, et al. Among authors: indapurkar a. J Pharmacol Toxicol Methods. 2022 Nov-Dec;118:107229. doi: 10.1016/j.vascn.2022.107229. Epub 2022 Nov 9. J Pharmacol Toxicol Methods. 2022. PMID: 36334898 Free article.
hERG block potencies for 5 positive control drugs obtained per ICH E14/S7B Q&As best practices: Impact of recording temperature and drug loss.
Alvarez Baron C, Thiebaud N, Ren M, Viatchenko-Karpinski S, Indapurkar A, King T, Matta MK, Ismaiel OA, Patel V, Mashaee M, Vicente J, Wu WW. Alvarez Baron C, et al. Among authors: indapurkar a. J Pharmacol Toxicol Methods. 2022 Sep-Oct;117:107193. doi: 10.1016/j.vascn.2022.107193. Epub 2022 Jul 2. J Pharmacol Toxicol Methods. 2022. PMID: 35792285 Free article.
Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation.
Rubiano A, Indapurkar A, Yokosawa R, Miedzik A, Rosenzweig B, Arefin A, Moulin CM, Dame K, Hartman N, Volpe DA, Matta MK, Hughes DJ, Strauss DG, Kostrzewski T, Ribeiro AJS. Rubiano A, et al. Among authors: indapurkar a. Clin Transl Sci. 2021 May;14(3):1049-1061. doi: 10.1111/cts.12969. Epub 2021 Apr 3. Clin Transl Sci. 2021. PMID: 33382907 Free PMC article.