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Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer's and small vessel disease pathologies.
Waller R, Narramore R, Simpson JE, Heath PR, Verma N, Tinsley M, Barnes JR, Haris HT, Henderson FE, Matthews FE, Richardson CD, Brayne C, Ince PG, Kalaria RN, Wharton SB; CFAS. Waller R, et al. Among authors: ince pg. Brain Pathol. 2021 May;31(3):e12928. doi: 10.1111/bpa.12928. Epub 2021 Feb 15. Brain Pathol. 2021. PMID: 33336479 Free PMC article.
Oxidative Glial Cell Damage Associated with White Matter Lesions in the Aging Human Brain.
Al-Mashhadi S, Simpson JE, Heath PR, Dickman M, Forster G, Matthews FE, Brayne C, Ince PG, Wharton SB; Medical Research Council Cognitive Function and Ageing Study. Al-Mashhadi S, et al. Among authors: ince pg. Brain Pathol. 2015 Sep;25(5):565-74. doi: 10.1111/bpa.12216. Epub 2014 Nov 20. Brain Pathol. 2015. PMID: 25311358 Free PMC article.
Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain.
Waller R, Murphy M, Garwood CJ, Jennings L, Heath PR, Chambers A, Matthews FE, Brayne C, Ince PG, Wharton SB, Simpson JE; Cognitive Function and Ageing Neuropathology Study Group. Waller R, et al. Among authors: ince pg. Glia. 2018 Nov;66(11):2316-2323. doi: 10.1002/glia.23465. Epub 2018 Aug 10. Glia. 2018. PMID: 30098078
Advanced Glycation End Product Formation in Human Cerebral Cortex Increases With Alzheimer-Type Neuropathologic Changes but Is Not Independently Associated With Dementia in a Population-Derived Aging Brain Cohort.
Chambers A, Bury JJ, Minett T, Richardson CD, Brayne C, Ince PG, Shaw PJ, Garwood CJ, Heath PR, Simpson JE, Matthews FE, Wharton SB. Chambers A, et al. Among authors: ince pg. J Neuropathol Exp Neurol. 2020 Sep 1;79(9):950-958. doi: 10.1093/jnen/nlaa064. J Neuropathol Exp Neurol. 2020. PMID: 32766675
Calcium dysregulation in relation to Alzheimer-type pathology in the ageing brain.
Garwood C, Faizullabhoy A, Wharton SB, Ince PG, Heath PR, Shaw PJ, Baxter L, Gelsthorpe C, Forster G, Matthews FE, Brayne C, Simpson JE; MRC Cognitive Function and Ageing Neuropathology Study Group. Garwood C, et al. Among authors: ince pg. Neuropathol Appl Neurobiol. 2013 Dec;39(7):788-99. doi: 10.1111/nan.12033. Neuropathol Appl Neurobiol. 2013. PMID: 23421725
Microinfarcts in an older population-representative brain donor cohort (MRC CFAS): Prevalence, relation to dementia and mobility, and implications for the evaluation of cerebral Small Vessel Disease.
Ince PG, Minett T, Forster G, Brayne C, Wharton SB; Medical Research Council Cognitive Function and Ageing Neuropathology Study. Ince PG, et al. Neuropathol Appl Neurobiol. 2017 Aug;43(5):409-418. doi: 10.1111/nan.12363. Epub 2016 Oct 28. Neuropathol Appl Neurobiol. 2017. PMID: 27664944 Free PMC article.
A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort.
Simpson JE, Ince PG, Matthews FE, Shaw PJ, Heath PR, Brayne C, Garwood C, Higginbottom A, Wharton SB; MRC Cognitive Function and Ageing Neuropathology Study Group. Simpson JE, et al. Among authors: ince pg. Neuropathol Appl Neurobiol. 2015 Jun;41(4):483-96. doi: 10.1111/nan.12202. Epub 2015 Apr 23. Neuropathol Appl Neurobiol. 2015. PMID: 25443110 Free PMC article.
302 results