Imawaka H - Search Results

1

The effect of continuous arterial infusion of gabexate mesilate (FOY-007) on experimental acute pancreatitis.

Satoh H, Harada M, Tashiro S, Shiroya T, Imawaka H, Machii K. Satoh H, et al. Among authors: imawaka h. J Med Invest. 2004 Aug;51(3-4):186-93. doi: 10.2152/jmi.51.186. J Med Invest. 2004. PMID: 15460905 Free article.

2

Prediction of human bioavailability from human oral administration data and animal pharmacokinetic data without data from intravenous administration of drugs in humans.

Imawaka H, Ito K, Kitamura Y, Sugiyama K, Sugiyama Y. Imawaka H, et al. Pharm Res. 2009 Aug;26(8):1881-9. doi: 10.1007/s11095-009-9902-6. Epub 2009 May 7. Pharm Res. 2009. PMID: 19418207

3

Kinetic study of the hepatobiliary transport of a new prostaglandin receptor agonist.

Imawaka H, Sugiyama Y. Imawaka H, et al. J Pharmacol Exp Ther. 1998 Mar;284(3):949-57. J Pharmacol Exp Ther. 1998. PMID: 9495854

4

Inclusion of human intravenous study data in new drug applications-impact of the Japanese guidance.

Imawaka H, Kusama M, Ito K, Ono S, Sugiyama Y. Imawaka H, et al. J Pharm Sci. 2012 Jul;101(7):2557-63. doi: 10.1002/jps.23135. Epub 2012 Apr 12. J Pharm Sci. 2012. PMID: 22499211

5

Comprehensive PBPK Model of Rifampicin for Quantitative Prediction of Complex Drug-Drug Interactions: CYP3A/2C9 Induction and OATP Inhibition Effects.

Asaumi R, Toshimoto K, Tobe Y, Hashizume K, Nunoya KI, Imawaka H, Lee W, Sugiyama Y. Asaumi R, et al. Among authors: imawaka h. CPT Pharmacometrics Syst Pharmacol. 2018 Mar;7(3):186-196. doi: 10.1002/psp4.12275. Epub 2018 Feb 5. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 29368402 Free PMC article.

6

Expanded Physiologically-Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction.

Asaumi R, Menzel K, Lee W, Nunoya KI, Imawaka H, Kusuhara H, Sugiyama Y. Asaumi R, et al. Among authors: imawaka h. CPT Pharmacometrics Syst Pharmacol. 2019 Nov;8(11):845-857. doi: 10.1002/psp4.12457. Epub 2019 Sep 5. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31420941 Free PMC article.

7

Analysis of Nonlinear Pharmacokinetics of a Highly Albumin-Bound Compound: Contribution of Albumin-Mediated Hepatic Uptake Mechanism.

Fukuchi Y, Toshimoto K, Mori T, Kakimoto K, Tobe Y, Sawada T, Asaumi R, Iwata T, Hashimoto Y, Nunoya KI, Imawaka H, Miyauchi S, Sugiyam Y. Fukuchi Y, et al. Among authors: imawaka h. J Pharm Sci. 2017 Sep;106(9):2704-2714. doi: 10.1016/j.xphs.2017.04.052. Epub 2017 Apr 30. J Pharm Sci. 2017. PMID: 28465151

8

Predicting successful/unsuccessful extrapolation for in vivo total clearance of model compounds with a variety of hepatic intrinsic metabolism and protein bindings in humans from pharmacokinetic data using chimeric mice with humanised liver.

Sawada T, Yamaura Y, Higuchi S, Imawaka H, Yamazaki H. Sawada T, et al. Among authors: imawaka h. Xenobiotica. 2020 May;50(5):526-535. doi: 10.1080/00498254.2019.1664791. Epub 2019 Sep 13. Xenobiotica. 2020. PMID: 31491346

9

Species Difference in Hydrolysis of an Ester-type Prodrug of Levodopa in Human and Animal Plasma: Different Contributions of Alpha-1 Acid Glycoprotein.

Kono K, Nunoya KI, Nakamura Y, Bi J, Mukunoki A, Takeo T, Nakagata N, Hitoshi M, Yamaura Y, Imawaka H, Watanabe H, Maruyama T. Kono K, et al. Among authors: imawaka h. Mol Pharm. 2021 May 3;18(5):1985-1991. doi: 10.1021/acs.molpharmaceut.0c01134. Epub 2021 Apr 16. Mol Pharm. 2021. PMID: 33861617

10

Design and synthesis of new orally active inhibitors of human neutrophil elastase.

Ohmoto K, Okuma M, Yamamoto T, Kijima H, Sekioka T, Kitagawa K, Yamamoto S, Tanaka K, Kawabata K, Sakata A, Imawaka H, Nakai H, Toda M. Ohmoto K, et al. Among authors: imawaka h. Bioorg Med Chem. 2001 May;9(5):1307-23. doi: 10.1016/s0968-0896(01)00007-4. Bioorg Med Chem. 2001. PMID: 11377188

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

19 results

Search Page