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Small-molecule WNK inhibition regulates cardiovascular and renal function.
Nat Chem Biol. 2016 Nov;12(11):896-898. doi: 10.1038/nchembio.2168. Epub 2016 Sep 5.
Nat Chem Biol. 2016.
PMID: 27595330
Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models.
Yamada K, Levell J, Yoon T, Kohls D, Yowe D, Rigel DF, Imase H, Yuan J, Yasoshima K, DiPetrillo K, Monovich L, Xu L, Zhu M, Kato M, Jain M, Idamakanti N, Taslimi P, Kawanami T, Argikar UA, Kunjathoor V, Xie X, Yagi YI, Iwaki Y, Robinson Z, Park HM.
Yamada K, et al. Among authors: imase h.
J Med Chem. 2017 Aug 24;60(16):7099-7107. doi: 10.1021/acs.jmedchem.7b00708. Epub 2017 Aug 3.
J Med Chem. 2017.
PMID: 28771350
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Discovery of a Novel Piperidine-Based Inhibitor of Cholesteryl Ester Transfer Protein (CETP) That Retains Activity in Hypertriglyceridemic Plasma.
Yamada K, Brousseau M, Honma W, Iimura A, Imase H, Iwaki Y, Kawanami T, LaSala D, Liang G, Mitani H, Nonomura K, Ohmori O, Pan M, Rigel DF, Umemura I, Yasoshima K, Zhu G, Mogi M.
Yamada K, et al. Among authors: imase h.
J Med Chem. 2017 Oct 26;60(20):8466-8481. doi: 10.1021/acs.jmedchem.7b00900. Epub 2017 Oct 16.
J Med Chem. 2017.
PMID: 29035537
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Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines.
Stefanetti G, Hu QY, Usera A, Robinson Z, Allan M, Singh A, Imase H, Cobb J, Zhai H, Quinn D, Lei M, Saul A, Adamo R, MacLennan CA, Micoli F.
Stefanetti G, et al. Among authors: imase h.
Angew Chem Int Ed Engl. 2015 Nov 2;54(45):13198-203. doi: 10.1002/anie.201506112. Epub 2015 Sep 9.
Angew Chem Int Ed Engl. 2015.
PMID: 26350581
Free PMC article.
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Highly enantioselective construction of axial chirality by palladium-catalyzed cycloisomerization of N-alkenyl arylethynylamides.
Imase H, Suda T, Shibata Y, Noguchi K, Hirano M, Tanaka K.
Imase H, et al.
Org Lett. 2009 Apr 16;11(8):1805-8. doi: 10.1021/ol900373z.
Org Lett. 2009.
PMID: 19281251
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Convergent and rapid assembly of substituted 2-pyridones through formation of N-alkenyl alkynylamides followed by gold-catalyzed cycloisomerization.
Imase H, Noguchi K, Hirano M, Tanaka K.
Imase H, et al.
Org Lett. 2008 Aug 21;10(16):3563-6. doi: 10.1021/ol801466f. Epub 2008 Jul 18.
Org Lett. 2008.
PMID: 18636742
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A new entry to Amaryllidaceae alkaloids from carbohydrates: total synthesis of (+)-vittatine.
Bohno M, Imase H, Chida N.
Bohno M, et al. Among authors: imase h.
Chem Commun (Camb). 2004 May 7;(9):1086-7. doi: 10.1039/b402762k. Epub 2004 Mar 30.
Chem Commun (Camb). 2004.
PMID: 15116197
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