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Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection.
Fujiwara S, Hoshizaki M, Ichida Y, Lex D, Kuroda E, Ishii KJ, Magi S, Okada M, Takao H, Gandou M, Imai H, Hara R, Herzog H, Yoshimura A, Okamura H, Penninger JM, Slutsky AS, Uhlig S, Kuba K, Imai Y. Fujiwara S, et al. Among authors: imai h, imai y. Nat Microbiol. 2019 Feb;4(2):258-268. doi: 10.1038/s41564-018-0289-1. Epub 2018 Nov 19. Nat Microbiol. 2019. PMID: 30455472
Angiotensin-converting enzyme 2 protects from severe acute lung failure.
Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C, Penninger JM. Imai Y, et al. Nature. 2005 Jul 7;436(7047):112-6. doi: 10.1038/nature03712. Nature. 2005. PMID: 16001071 Free PMC article.
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury.
Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C, Penninger JM. Kuba K, et al. Among authors: imai y. Nat Med. 2005 Aug;11(8):875-9. doi: 10.1038/nm1267. Epub 2005 Jul 10. Nat Med. 2005. PMID: 16007097 Free PMC article.
CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin.
Ichikawa A, Kuba K, Morita M, Chida S, Tezuka H, Hara H, Sasaki T, Ohteki T, Ranieri VM, dos Santos CC, Kawaoka Y, Akira S, Luster AD, Lu B, Penninger JM, Uhlig S, Slutsky AS, Imai Y. Ichikawa A, et al. Among authors: imai y. Am J Respir Crit Care Med. 2013 Jan 1;187(1):65-77. doi: 10.1164/rccm.201203-0508OC. Epub 2012 Nov 9. Am J Respir Crit Care Med. 2013. PMID: 23144331 Free PMC article.
The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza.
Morita M, Kuba K, Ichikawa A, Nakayama M, Katahira J, Iwamoto R, Watanebe T, Sakabe S, Daidoji T, Nakamura S, Kadowaki A, Ohto T, Nakanishi H, Taguchi R, Nakaya T, Murakami M, Yoneda Y, Arai H, Kawaoka Y, Penninger JM, Arita M, Imai Y. Morita M, et al. Among authors: imai y. Cell. 2013 Mar 28;153(1):112-25. doi: 10.1016/j.cell.2013.02.027. Epub 2013 Mar 7. Cell. 2013. PMID: 23477864 Free article.
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury.
Imai Y, Kuba K, Neely GG, Yaghubian-Malhami R, Perkmann T, van Loo G, Ermolaeva M, Veldhuizen R, Leung YH, Wang H, Liu H, Sun Y, Pasparakis M, Kopf M, Mech C, Bavari S, Peiris JS, Slutsky AS, Akira S, Hultqvist M, Holmdahl R, Nicholls J, Jiang C, Binder CJ, Penninger JM. Imai Y, et al. Cell. 2008 Apr 18;133(2):235-49. doi: 10.1016/j.cell.2008.02.043. Cell. 2008. PMID: 18423196 Free PMC article.
4,549 results