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A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke.
Lyden PD, Diniz MA, Bosetti F, Lamb J, Nagarkatti KA, Rogatko A, Kim S, Cabeen RP, Koenig JI, Akhter K, Arbab AS, Avery BD, Beatty HE, Bibic A, Cao S, Simoes Braga Boisserand L, Chamorro A, Chauhan A, Diaz-Perez S, Dhandapani K, Dhanesha N, Goh A, Herman AL, Hyder F, Imai T, Johnson CW, Khan MB, Kamat P, Karuppagounder SS, Kumskova M, Mihailovic JM, Mandeville JB, Morais A, Patel RB, Sanganahalli BG, Smith C, Shi Y, Sutariya B, Thedens D, Qin T, Velazquez SE, Aronowski J, Ayata C, Chauhan AK, Leira EC, Hess DC, Koehler RC, McCullough LD, Sansing LH. Lyden PD, et al. Among authors: imai t. Sci Transl Med. 2023 Sep 20;15(714):eadg8656. doi: 10.1126/scitranslmed.adg8656. Epub 2023 Sep 20. Sci Transl Med. 2023. PMID: 37729432 Clinical Trial.
The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results.
Lyden PD, Bosetti F, Diniz MA, Rogatko A, Koenig JI, Lamb J, Nagarkatti KA, Cabeen RP, Hess DC, Kamat PK, Khan MB, Wood K, Dhandapani K, Arbab AS, Leira EC, Chauhan AK, Dhanesha N, Patel RB, Kumskova M, Thedens D, Morais A, Imai T, Qin T, Ayata C, Boisserand LSB, Herman AL, Beatty HE, Velazquez SE, Diaz-Perez S, Sanganahalli BG, Mihailovic JM, Hyder F, Sansing LH, Koehler RC, Lannon S, Shi Y, Karuppagounder SS, Bibic A, Akhter K, Aronowski J, McCullough LD, Chauhan A, Goh A; SPAN Investigators. Lyden PD, et al. Among authors: imai t. Stroke. 2022 May;53(5):1802-1812. doi: 10.1161/STROKEAHA.121.038047. Epub 2022 Mar 31. Stroke. 2022. PMID: 35354299 Free PMC article. Clinical Trial.
CADASIL mutations sensitize the brain to ischemia via spreading depolarizations and abnormal extracellular potassium homeostasis.
Oka F, Lee JH, Yuzawa I, Li M, von Bornstaedt D, Eikermann-Haerter K, Qin T, Chung DY, Sadeghian H, Seidel JL, Imai T, Vuralli D, Platt RM, Nelson MT, Joutel A, Sakadzic S, Ayata C. Oka F, et al. Among authors: imai t. J Clin Invest. 2022 Apr 15;132(8):e149759. doi: 10.1172/JCI149759. J Clin Invest. 2022. PMID: 35202003 Free PMC article.
Predicting Trabectedin Efficacy in Soft Tissue Sarcoma: Inflammatory Biomarker Analysis.
Imai T, Kojima Y, Shimoi T, Aiba H, Okuma HS, Saito A, Kita S, Yamamoto K, Maejima A, Nishikawa T, Sudo K, Noguchi E, Yoshida A, Matsui Y, Iwata S, Kobayashi E, Kawai A, Udagawa R, Fujiwara Y, Yonemori K. Imai T, et al. Anticancer Res. 2024 May;44(5):2125-2132. doi: 10.21873/anticanres.17018. Anticancer Res. 2024. PMID: 38677749
A mouse model of autoimmune inner ear disease without endolymphatic hydrops.
Harada S, Koyama Y, Imai T, Yoshioka Y, Sumi T, Inohara H, Shimada S. Harada S, et al. Among authors: imai t. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 25;1870(5):167198. doi: 10.1016/j.bbadis.2024.167198. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38670439 Free article.
3,205 results