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KUS121, a VCP modulator, has an ameliorating effect on acute and chronic heart failure without calcium loading via maintenance of intracellular ATP levels.
Tsuji S, Otani C, Horie T, Watanabe S, Baba O, Sowa N, Ide Y, Kashiwa A, Makiyama T, Imai H, Nakashima Y, Yamasaki T, Xu S, Matsushita K, Suzuki K, Zou F, Kume E, Hasegawa K, Kimura T, Kakizuka A, Ono K. Tsuji S, et al. Among authors: imai h. Biomed Pharmacother. 2024 Jan;170:115850. doi: 10.1016/j.biopha.2023.115850. Epub 2023 Dec 12. Biomed Pharmacother. 2024. PMID: 38091636 Free article.
Excess intracellular ATP causes neuropathic pain following spinal cord injury.
Nakajima N, Ohnishi Y, Yamamoto M, Setoyama D, Imai H, Takenaka T, Matsumoto M, Hosomi K, Saitoh Y, Furue H, Kishima H. Nakajima N, et al. Among authors: imai h. Cell Mol Life Sci. 2022 Aug 16;79(9):483. doi: 10.1007/s00018-022-04510-z. Cell Mol Life Sci. 2022. PMID: 35972649 Free PMC article.
Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo.
Kobayashi H, Matsuda Y, Hitomi T, Okuda H, Shioi H, Matsuda T, Imai H, Sone M, Taura D, Harada KH, Habu T, Takagi Y, Miyamoto S, Koizumi A. Kobayashi H, et al. Among authors: imai h. J Am Heart Assoc. 2015 Jun 30;4(7):e002146. doi: 10.1161/JAHA.115.002146. J Am Heart Assoc. 2015. PMID: 26126547 Free PMC article.
2,684 results