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Crystal structures of Staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate.
J Med Chem. 2004 Mar 11;47(6):1325-8. doi: 10.1021/jm034188j.
J Med Chem. 2004.
PMID: 14998322
A novel three-component one-pot synthesis of 1H-imidazol-4-yl-pyridines.
Illgen K, Nerdinger S, Behnke D, Friedrich C.
Illgen K, et al.
Org Lett. 2005 Jan 6;7(1):39-42. doi: 10.1021/ol0480269.
Org Lett. 2005.
PMID: 15624972
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Solution phase parallel synthesis and evaluation of MAPK inhibitory activities of close structural analogues of a Ras pathway modulator.
Lu Y, Sakamuri S, Chen QZ, Keng YF, Khazak V, Illgen K, Schabbert S, Weber L, Menon SR.
Lu Y, et al. Among authors: illgen k.
Bioorg Med Chem Lett. 2004 Aug 2;14(15):3957-62. doi: 10.1016/j.bmcl.2004.05.048.
Bioorg Med Chem Lett. 2004.
PMID: 15225706
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Simulated molecular evolution in a full combinatorial library.
Illgen K, Enderle T, Broger C, Weber L.
Illgen K, et al.
Chem Biol. 2000 Jun;7(6):433-41. doi: 10.1016/s1074-5521(00)00122-8.
Chem Biol. 2000.
PMID: 10873838
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