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Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice.
Grycová A, Joo H, Maier V, Illés P, Vyhlídalová B, Poulíková K, Sládeková L, Nádvorník P, Vrzal R, Zemánková L, Pečinková P, Poruba M, Zapletalová I, Večeřa R, Anzenbacher P, Ehrmann J, Ondra P, Jung JW, Mani S, Dvořák Z. Grycová A, et al. Among authors: illes p. J Med Chem. 2022 May 12;65(9):6859-6868. doi: 10.1021/acs.jmedchem.2c00208. Epub 2022 Apr 13. J Med Chem. 2022. PMID: 35416668
Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics.
Li H, Illés P, Karunaratne CV, Nordstrøm LU, Luo X, Yang A, Qiu Y, Kurland IJ, Lukin DJ, Chen W, Jiskrová E, Krasulová K, Pečinková P, DesMarais VM, Liu Q, Albanese JM, Akki A, Longo M, Coffin B, Dou W, Mani S, Dvořák Z. Li H, et al. Among authors: illes p. Bioorg Chem. 2021 Apr;109:104661. doi: 10.1016/j.bioorg.2021.104661. Epub 2021 Jan 22. Bioorg Chem. 2021. PMID: 33636438 Free PMC article.
Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases.
Michaudel C, Danne C, Agus A, Magniez A, Aucouturier A, Spatz M, Lefevre A, Kirchgesner J, Rolhion N, Wang Y, Lavelle A, Galbert C, Da Costa G, Poirier M, Lapière A, Planchais J, Nádvorník P, Illes P, Oeuvray C, Creusot L, Michel ML, Benech N, Bourrier A, Nion-Larmurier I, Landman C, Richard ML, Emond P, Seksik P, Beaugerie L, Arguello RR, Moulin D, Mani S, Dvorák Z, Bermúdez-Humarán LG, Langella P, Sokol H. Michaudel C, et al. Among authors: illes p. Gut. 2023 Jul;72(7):1296-1307. doi: 10.1136/gutjnl-2022-327337. Epub 2022 Oct 21. Gut. 2023. PMID: 36270778 Free PMC article.
372 results