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How the Cobra Got Its Flesh-Eating Venom: Cytotoxicity as a Defensive Innovation and Its Co-Evolution with Hooding, Aposematic Marking, and Spitting.
Panagides N, Jackson TN, Ikonomopoulou MP, Arbuckle K, Pretzler R, Yang DC, Ali SA, Koludarov I, Dobson J, Sanker B, Asselin A, Santana RC, Hendrikx I, van der Ploeg H, Tai-A-Pin J, van den Bergh R, Kerkkamp HM, Vonk FJ, Naude A, Strydom MA, Jacobsz L, Dunstan N, Jaeger M, Hodgson WC, Miles J, Fry BG. Panagides N, et al. Among authors: ikonomopoulou mp. Toxins (Basel). 2017 Mar 13;9(3):103. doi: 10.3390/toxins9030103. Toxins (Basel). 2017. PMID: 28335411 Free PMC article.
Immune drug discovery from venoms.
Jimenez R, Ikonomopoulou MP, Lopez JA, Miles JJ. Jimenez R, et al. Among authors: ikonomopoulou mp. Toxicon. 2018 Jan;141:18-24. doi: 10.1016/j.toxicon.2017.11.006. Epub 2017 Nov 21. Toxicon. 2018. PMID: 29170055 Review.
Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis).
Goldenberg J, Cipriani V, Jackson TNW, Arbuckle K, Debono J, Dashevsky D, Panagides N, Ikonomopoulou MP, Koludarov I, Li B, Santana RC, Nouwens A, Jones A, Hay C, Dunstan N, Allen L, Bush B, Miles JJ, Ge L, Kwok HF, Fry BG. Goldenberg J, et al. Among authors: ikonomopoulou mp. Comp Biochem Physiol C Toxicol Pharmacol. 2018 Feb;205:53-61. doi: 10.1016/j.cbpc.2018.01.001. Epub 2018 Jan 17. Comp Biochem Physiol C Toxicol Pharmacol. 2018. PMID: 29353015 Free article.
Extensive Variation in the Activities of Pseudocerastes and Eristicophis Viper Venoms Suggests Divergent Envenoming Strategies Are Used for Prey Capture.
Op den Brouw B, Coimbra FCP, Bourke LA, Huynh TM, Vlecken DHW, Ghezellou P, Visser JC, Dobson JS, Fernandez-Rojo MA, Ikonomopoulou MP, Casewell NR, Ali SA, Fathinia B, Hodgson WC, Fry BG. Op den Brouw B, et al. Among authors: ikonomopoulou mp. Toxins (Basel). 2021 Feb 2;13(2):112. doi: 10.3390/toxins13020112. Toxins (Basel). 2021. PMID: 33540884 Free PMC article.
ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations.
Moral-Sanz J, Fernandez-Rojo MA, Potriquet J, Mukhopadhyay P, Brust A, Wilhelm P, Smallwood TB, Clark RJ, Fry BG, Alewood PF, Waddell N, Miles JJ, Mulvenna JP, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: ikonomopoulou mp. Toxins (Basel). 2021 Feb 14;13(2):146. doi: 10.3390/toxins13020146. Toxins (Basel). 2021. PMID: 33672955 Free PMC article.
Immunological Responses to Envenomation.
Ryan RYM, Seymour J, Loukas A, Lopez JA, Ikonomopoulou MP, Miles JJ. Ryan RYM, et al. Among authors: ikonomopoulou mp. Front Immunol. 2021 May 10;12:661082. doi: 10.3389/fimmu.2021.661082. eCollection 2021. Front Immunol. 2021. PMID: 34040609 Free PMC article. Review.
The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E.
Moral-Sanz J, Fernandez-Rojo MA, Colmenarejo G, Kurdyukov S, Brust A, Ragnarsson L, Andersson Å, Vila SF, Cabezas-Sainz P, Wilhelm P, Vela-Sebastián A, Fernández-Carrasco I, Chin YKY, López-Mancheño Y, Smallwood TB, Clark RJ, Fry BG, King GF, Ramm GA, Alewood PF, Lewis RJ, Mulvenna JP, Boyle GM, Sanchez LE, Neely GG, Miles JJ, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: ikonomopoulou mp. Br J Pharmacol. 2022 Oct;179(20):4878-4896. doi: 10.1111/bph.15923. Epub 2022 Jul 29. Br J Pharmacol. 2022. PMID: 35818835 Free article.
Functional and Proteomic Insights into Aculeata Venoms.
Dashevsky D, Baumann K, Undheim EAB, Nouwens A, Ikonomopoulou MP, Schmidt JO, Ge L, Kwok HF, Rodriguez J, Fry BG. Dashevsky D, et al. Among authors: ikonomopoulou mp. Toxins (Basel). 2023 Mar 16;15(3):224. doi: 10.3390/toxins15030224. Toxins (Basel). 2023. PMID: 36977115 Free PMC article.
33 results