Ikonen E - Search Results

1

Cln5-deficiency in mice leads to microglial activation, defective myelination and changes in lipid metabolism.

Schmiedt ML, Blom T, Blom T, Kopra O, Wong A, von Schantz-Fant C, Ikonen E, Kuronen M, Jauhiainen M, Cooper JD, Jalanko A. Schmiedt ML, et al. Among authors: ikonen e. Neurobiol Dis. 2012 Apr;46(1):19-29. doi: 10.1016/j.nbd.2011.12.009. Epub 2011 Dec 13. Neurobiol Dis. 2012. PMID: 22182690

2

Dissection of the molecular consequences of a double mutation causing a human lysosomal disease.

Riikonen A, Ikonen E, Sormunen R, Lehto VP, Peltonen L, Jalanko A. Riikonen A, et al. Among authors: ikonen e. DNA Cell Biol. 1994 Mar;13(3):257-64. doi: 10.1089/dna.1994.13.257. DNA Cell Biol. 1994. PMID: 8172656

3

Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane.

Lusa S, Blom TS, Eskelinen EL, Kuismanen E, Månsson JE, Simons K, Ikonen E. Lusa S, et al. Among authors: ikonen e. J Cell Sci. 2001 May;114(Pt 10):1893-900. doi: 10.1242/jcs.114.10.1893. J Cell Sci. 2001. PMID: 11329376

4

Mass spectrometric analysis reveals an increase in plasma membrane polyunsaturated phospholipid species upon cellular cholesterol loading.

Blom TS, Koivusalo M, Kuismanen E, Kostiainen R, Somerharju P, Ikonen E. Blom TS, et al. Among authors: ikonen e. Biochemistry. 2001 Dec 4;40(48):14635-44. doi: 10.1021/bi0156714. Biochemistry. 2001. PMID: 11724577

5

Secretion of sterols and the NPC2 protein from primary astrocytes.

Mutka AL, Lusa S, Linder MD, Jokitalo E, Kopra O, Jauhiainen M, Ikonen E. Mutka AL, et al. Among authors: ikonen e. J Biol Chem. 2004 Nov 19;279(47):48654-62. doi: 10.1074/jbc.M405345200. Epub 2004 Sep 7. J Biol Chem. 2004. PMID: 15355983 Free article.

6

Defective insulin receptor activation and altered lipid rafts in Niemann-Pick type C disease hepatocytes.

Vainio S, Bykov I, Hermansson M, Jokitalo E, Somerharju P, Ikonen E. Vainio S, et al. Among authors: ikonen e. Biochem J. 2005 Nov 1;391(Pt 3):465-72. doi: 10.1042/BJ20050460. Biochem J. 2005. PMID: 15943586 Free PMC article.

7

Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction.

Ahtiainen L, Kolikova J, Mutka AL, Luiro K, Gentile M, Ikonen E, Khiroug L, Jalanko A, Kopra O. Ahtiainen L, et al. Among authors: ikonen e. Neurobiol Dis. 2007 Oct;28(1):52-64. doi: 10.1016/j.nbd.2007.06.012. Epub 2007 Jun 23. Neurobiol Dis. 2007. PMID: 17656100

8

Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain.

Mutka AL, Haapanen A, Käkelä R, Lindfors M, Wright AK, Inkinen T, Hermansson M, Rokka A, Corthals G, Jauhiainen M, Gillingwater TH, Ikonen E, Tyynelä J. Mutka AL, et al. Among authors: ikonen e. J Neurochem. 2010 Jan;112(1):193-203. doi: 10.1111/j.1471-4159.2009.06440.x. Epub 2009 Oct 20. J Neurochem. 2010. PMID: 19845830 Free article.

9

FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages.

Blom T, Bäck N, Mutka AL, Bittman R, Li Z, de Lera A, Kovanen PT, Diczfalusy U, Ikonen E. Blom T, et al. Among authors: ikonen e. Circ Res. 2010 Mar 5;106(4):720-9. doi: 10.1161/CIRCRESAHA.109.204396. Epub 2010 Jan 7. Circ Res. 2010. PMID: 20056921 Free PMC article.

10

Niemann-Pick C1 modulates hepatic triglyceride metabolism and its genetic variation contributes to serum triglyceride levels.

Uronen RL, Lundmark P, Orho-Melander M, Jauhiainen M, Larsson K, Siegbahn A, Wallentin L, Zethelius B, Melander O, Syvänen AC, Ikonen E. Uronen RL, et al. Among authors: ikonen e. Arterioscler Thromb Vasc Biol. 2010 Aug;30(8):1614-20. doi: 10.1161/ATVBAHA.110.207191. Epub 2010 May 20. Arterioscler Thromb Vasc Biol. 2010. PMID: 20489167

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